0. DOCID:14324 SCORE: 0.00345371999230803
DOCNO: 2777441
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: T Y Chuang TY
AUTHOR: J Tse J
AUTHOR: D J Cripps DJ
AFFILIATION: Dermatology Section, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of dermatology.
COUNTRY: UNITED STATES
TITLE: A preliminary study on the link between PUVA and skin cancer.
PUBDATE: 19890901
One hundred four psoriatic patients who had 8-methoxypsoralen-ultraviolet light A (PUVA) treatment between 1975-1987 were investigated to determine if skin cancer had ever occurred during or after the therapeutic period. Incidence data of skin cancer was applied to this group of patients to measure the expected number of patients with skin cancer. The significance of observed number versus expected of PUVA-treated patients with skin cancer was analyzed. The authors did not observe a significant increase of patients with skin cancer.


1. DOCID:14297 SCORE: 0.00345371456735787
DOCNO: 3343036
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Mizumoto K
AUTHOR: T Inagaki T
AUTHOR: M Koizumi M
AUTHOR: M Uemura M
AUTHOR: M Ogawa M
AUTHOR: S Kitazawa S
AUTHOR: M Tsutsumi M
AUTHOR: M Toyokawa M
AUTHOR: Y Konishi Y
AFFILIATION: Department of Oncological Pathology, Nara Medical College, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Human pathology.
COUNTRY: UNITED STATES
TITLE: Early pancreatic duct adenocarcinoma.
PUBDATE: 19880201
A 68-year-old Japanese woman presented with complaints of appetite and weight loss. Early pancreatic duct adenocarcinoma was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP), which revealed partial obstruction of the main pancreatic duct. Pancreatoduodenectomy with lymph node dissection was performed. Macroscopically, no pancreatic tumor was detected. Histologically, the pancreatic lesion showed continuous changes consisting of duct epithelial cell hyperplasia, carcinoma in situ, and invasive carcinoma. Immunohistochemical stains for carcinoembryonic antigen and CA19-9 were positive in cancer cells.


2. DOCID:15942 SCORE: 0.00313239235937739
DOCNO: 2682365
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, X-Ray Computed
DESCRIPTOR: Ultrasonography
QUALIFIER: diagnosis
AUTHOR: A Paduos A
AUTHOR: G Falcetto G
AUTHOR: P Alluminio P
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Use of computerized axial tomography and transrectal echography in the preoperative evaluation of cancer of the rectum]
PUBDATE: 19890701
Eight patients were subjected to two types of preoperative investigation in the attempt to stage cancers localised in the final 13 cm of the rectum: CT scan and transrectal echography. CT scan was used to assess infiltration of perirectal tissues and any lymph node metastases. Echography was used to examine the degree of infiltration of the rectal wall. Patients were then submitted to surgery. The predictivity of these studies proved sufficiently high. 7 Miles amputations and 1 anterior resection were carried out. One case only in which the scan did not show signs of parietal lesions presented two perirectal lymph node metastases. If refined further, these evaluations will therefore influence surgical tactics.


3. DOCID:15733 SCORE: 0.0030292197594594
DOCNO: 3764077
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Self-Help Groups
DESCRIPTOR: Social Adjustment
QUALIFIER: rehabilitation
AUTHOR: D Schaeffer D
AUTHOR: V Garms-Homolová V
PUBTYPE: Journal Article
JOURNALTITLE: Die Rehabilitation.
COUNTRY: GERMANY, WEST
TITLE: [Significance of self-help groups for psychosocial rehabilitation in cancer]
PUBDATE: 19860801
Experiences of cancer patients' self-help groups can provide impulses for the programming of rehabilitation measures. Exemplary is the information work (information procurement and distribution) of these groups. Problems emanating from disturbed interpersonal relationships and the stigma of the disease are dealt with implicitly rather than explicitly, with only certain patients, however, benefitting selectively from this kind of coping, depending on the stage of the disease and on their social context. The groups succeed in substituting missing or disturbed interpersonal relationships, they sometimes however find it difficult to ward off those aspects of isolation that have arisen with the onset of the disease. These difficulties weigh on other parts of the informal network, especially on the families.


4. DOCID:13949 SCORE: 0.00284508886097436
DOCNO: 2546666
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: A Selypes A
AUTHOR: A László A
AFFILIATION: Department of Hygiene and Epidemiology, Albert Szent-György Medical University, Szeged, Hungary.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Chromosome changes in a brain metastasis of a large cell lung cancer.
PUBDATE: 19890601
Direct chromosome preparations were made on a brain metastasis of a large cell lung cancer from a 46-year-old female patient. In the 169 cells examined, the modal chromosomes number was 73, and the majority (53.2%) of mitoses were in the near-triploid region. The tumor cells showed considerable heterogeneity in chromosome number and content. Chromosomes 3, 4, and 5 were the most frequently involved in aberrations. The mean number of unidentified marker chromosomes was five per mitosis.


5. DOCID:15562 SCORE: 0.00275888305554095
DOCNO: 3700165
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: K Sjövall K
AUTHOR: C Silfverswärd C
AUTHOR: N Einhorn N
PUBTYPE: Journal Article
JOURNALTITLE: International journal of radiation oncology, biology, physics.
COUNTRY: UNITED STATES
TITLE: Ovarian cancer: the challenge of local tumor control and its impact on survival.
PUBDATE: 19860401
To achieve better understanding of the factors influencing local control of ovarian cancer, an analysis of failure in early stages of ovarian carcinoma has been carried out. The material consisted of 185 patients diagnosed in early stages; 40 of them failed in their disease, 17 with local recurrence, 23 with distant metastases. The material was analyzed with respect to age, histology, grade, size and surface of the tumor, the surgical procedure and treatment modalities, and the time between treatment and recurrence, and recurrence and death. In the analysis, both the behavior of the ovarian cancer tumor and the pattern of failure was shown to be different for each histological group.


6. DOCID:15351 SCORE: 0.00271292579708905
DOCNO: 3280595
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: therapeutic use
AUTHOR: G Bartfai G
AFFILIATION: Department of Obstetrics and Gynecology, University Medical School of Szeged, Hungary.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Human reproduction (Oxford, England)
COUNTRY: ENGLAND
TITLE: Clinical applications of gonadotrophin-releasing hormone and its analogues.
PUBDATE: 19880101
The clinical applications of GnRH and its analogues are discussed. GnRH can be used diagnostically to assess the releasable pool of LH and the status of gonadotrophin secretion. Clinically it can be used to induce follicle growth and ovulation in patients with hypogonadotrophic amenorrhoea, especially when given in pulsatile form, and there are reports that it might also stimulate spermatogenesis in men with hypogonadotrophic hypogonadism. Analogues are proving valuable in the treatment of precocious puberty, but are not yet practical for contraception. They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for in-vitro fertilization.


7. DOCID:12953 SCORE: 0.00252691048104613
DOCNO: 2520043
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: V K Khanijow VK
AUTHOR: U Prasad U
AUTHOR: C M Chang CM
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Malaysia.
COUNTRY: MALAYSIA
TITLE: Chemotherapy in nasopharyngeal carcinoma: review of results at University Hospital, Kuala Lumpur.
PUBDATE: 19891201
Nasopharyngeal carcinoma (NPC) is one of the commonest presentation of head and neck cancers in Malaysia, especially in the Chinese. The standard treatment is radical radiotherapy to the post-nasal space and the neck. Chemotherapy is given to patients with primary advanced disease and to patients with recurrence. The study reviews results of chemotherapy given to 33 patients at the University Hospital, Kuala Lumpur, over the last four years.


8. DOCID:13213 SCORE: 0.00249750979131212
DOCNO: 2486487
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiation effects
QUALIFIER: methods
AUTHOR: G Newman G
AUTHOR: J Bell J
AUTHOR: P Goddard P
AUTHOR: J A Bullimore JA
AFFILIATION: Bristol Radiotherapy and Oncology Centre.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical oncology (Royal College of Radiologists (Great Britain))
COUNTRY: ENGLAND
TITLE: Pulmonary changes in breast cancer patients treated by three different radiotherapy techniques.
PUBDATE: 19891101
Twenty eight patients with breast cancer were studied by CT, perfusion scans and pulmonary function tests to assess the extent of post-irradiation changes. The patients had been treated by three treatment techniques using either two, three or four fields with different amounts of lung included in the target volume. The most extensive changes were seen in those patients who received treatment to the mediastinum.


9. DOCID:14726 SCORE: 0.00248466956807694
DOCNO: 3032535
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: genetics
QUALIFIER: pathology
QUALIFIER: genetics
AUTHOR: R C Kurtz RC
AUTHOR: S S Sternberg SS
AUTHOR: H H Miller HH
AUTHOR: J J Decosse JJ
PUBTYPE: Journal Article
JOURNALTITLE: Digestive diseases and sciences.
COUNTRY: UNITED STATES
TITLE: Upper gastrointestinal neoplasia in familial polyposis.
PUBDATE: 19870501
Upper gastrointestinal (UGI) endoscopy was performed in 41 asymptomatic American patients with familial polyposis to assess the prevalence of gastric and duodenal polyps and to characterize their pathological features. Eighteen patients (44%) had UGI endoscopic abnormalities. Six patients had both gastric and duodenal lesions. Eight patients had only gastric polyps, and four had duodenal polyps only. The presence of other extracolonic expressions of polyposis had a suggestive but statistically insignificant correlation with UGI polyps. Patients with familial polyposis and duodenal adenomatous polyps are at high risk for the development of periampullary cancer; screening and identification of these individuals is recommended.


10. DOCID:13191 SCORE: 0.00243942099628123
DOCNO: 3396950
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrointestinal Motility
QUALIFIER: physiopathology
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: B N Catchpole BN
AFFILIATION: Department of Surgery, St Mark's Hospital, London.
PUBTYPE: Journal Article
JOURNALTITLE: Gut.
COUNTRY: ENGLAND
TITLE: Motor pattern of the left colon before and after surgery for rectal cancer: possible implications in other disorders.
PUBDATE: 19880501
The motility of the descending colon was studied in nine patients before and after resection of the rectum for cancer. This operation parasympathectomises and generally also sympathectomises the remaining left colon. Motor activity was significantly reduced by sleep before and after surgery. There was also a reduction in awake motility after surgery which is attributed to extrinsic denervation. The reduced motility may explain the increased frequency of motions passed after surgery.


11. DOCID:15664 SCORE: 0.0020471162590754
DOCNO: 3709430
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: J Overnell J
PUBTYPE: Journal Article
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Occurrence of cadmium in crabs (Cancer pagurus) and the isolation and properties of cadmium metallothionein.
PUBDATE: 19860301
The occurrence of high cadmium levels in the digestive gland (hepatopancreas) of the crab Cancer pagurus is reviewed and its possible significance to human health is discussed. Previous attempts to isolate this cadmium in its native form are briefly reviewed and the present method used in this laboratory to isolate crab cadmium metallothionein is described. Quantitative amino acid analysis of the purified protein suggests that it has a total of 55 residues, including 19 Cys, and a molecular weight of approximately 5800. This yields an extinction coefficient at 220 nm for the protein in HCl, pH 1.5, of 50,000 and at 250 nm for the native cadmium protein in Tris-HCl, pH 8.4, of 92,000.


12. DOCID:15568 SCORE: 0.00203201470742524
DOCNO: 3024582
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: I Nakarai I
AUTHOR: T Ueno T
AUTHOR: A Hayashi A
AUTHOR: A Shinoda A
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Combination therapy of high-dose carboquone and OK-432 in unresectable non-small cell lung cancer]
PUBDATE: 19861201
A combination of OK-432 and high-dose Carboquone (12-22 mg/m2) was administered to 17 patients with unresectable non-small cell lung cancer. The response rate was 42.9% (CR-1, PR-5) among 14 patients in whom measurement of tumor diameter was possible. With regard to hematologic adverse effects, 13 patients had a WBC count of less than 3,000, and 6 patients had a platelet count of less than 50,000. Duration of WBC nadir was not longer than 3 days, and there were no cases of infectious complication or bleeding tendency. Other side effects were all transient.


13. DOCID:15549 SCORE: 0.0020320145912832
DOCNO: 3769743
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: mortality
AUTHOR: H T Yu HT
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Prognosis of breast cancer--20 years experience in radical mastectomy]
PUBDATE: 19860301
From 1958 to 1982, 1,035 patients with breast cancer were treated by operation in our hospital. The follow up rate was 100% and 804 were followed for more than 5 years. Radical mastectomy was performed in 695 of the 804 patients, the rest were treated by simple mastectomy, modified radical mastectomy and extended radical mastectomy. The 5, 10, 15 and 20 year survival rates were 71.8%, 58.2%, 48.8% and 41.8%. According to the UICC TNM classification, the 5, 10, 15 and 20 year survival rates of stage I were 84.5%, 77.0%, 58.3% and 75.0%, of stage II, 72.8%, 57.4%, 53.5% and 58.8%, and of stage III, were 55.3%, 44.7%, 36.5% and 8.0%, respectively.


14. DOCID:13124 SCORE: 0.00202216148454922
DOCNO: 3758366
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: analysis
AUTHOR: R J Steele RJ
AUTHOR: O Eremin O
AUTHOR: M Brown M
AUTHOR: R A Hawkins RA
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Oestrogen receptor concentration and macrophage infiltration in human breast cancer.
PUBDATE: 19860901
Oestrogen receptor concentration and percentage macrophage content were estimated in 40 human primary breast cancers. Macrophages were identified by Fc (IgG) receptor expression and by the presence of a macrophage-associated antigen. A significant inverse correlation between receptor concentration and macrophage content was found, and this was strengthened by correcting receptor level for tumour cellularity.