0. DOCID:19584 SCORE: 0.00582941961402019
DOCNO: 1555196
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sister Chromatid Exchange
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: L Lukovic L
AUTHOR: J Milasin J
AFFILIATION: Institute of Biology and Human Genetics, University of Belgrade School of Medicine and Dentistry, Yugoslavia.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Sister chromatid exchanges in patients with carcinoma in situ of cervix uteri.
PUBDATE: 19920301
Sister chromatid exchange (SCE) was analyzed in lymphocytes of 21 patients with carcinoma in situ of cervix uteri and 19 control subjects. The mean SCE frequencies were 8.92 +/- 0.31 (n = 417) and 6.94 +/- 0.23, (n = 375) per metaphase in patients and controls, respectively. The increase of SCE levels in cancer patients was highly significant in respect to controls (p less than 0.001). Together with data of other authors in patients with precancerous and cancerous lesions of the cervix, our results suggest that there is no correlation between SCE rate and severity of cancerous lesions.


1. DOCID:19260 SCORE: 0.00388820941834377
DOCNO: 2258086
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pregnancy Complications, Neoplastic
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: M Shaves M
AUTHOR: R R Kamps RR
AUTHOR: L R Laufman LR
AUTHOR: C D Runowicz CD
AFFILIATION: Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10461.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: A successful term pregnancy following the systemic and intraperitoneal administration of cisplatin chemotherapy.
PUBDATE: 19901201
The advent of successful chemotherapy has improved the prognosis and long-term disease-free survival for many patients with a variety of malignancies. Preservation of reproductive function in female patients is now possible with conservative surgery in certain selected malignancies. Successful pregnancies following chemotherapy or ovarian cancer have been reported. This is the first reported case of a term pregnancy following the systemic and intraperitoneal administration of cisplatin chemotherapy in the treatment of ovarian cancer.


2. DOCID:23103 SCORE: 0.00353139372821189
DOCNO: 8912548
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: drug therapy
QUALIFIER: blood
AUTHOR: G J Rustin GJ
AUTHOR: T G Quinnell TG
AUTHOR: J Johnson J
AUTHOR: H Clarke H
AUTHOR: A E Nelstrop AE
AUTHOR: W Bollag W
AFFILIATION: Department of Medical Oncology, Mount Vernon Centre for Cancer Treatment, Mount Vernon Hospital, Northwood, Middlesex, UK.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: British journal of cancer.
COUNTRY: SCOTLAND
TITLE: Trial of isotretinoin and calcitriol monitored by CA 125 in patients with ovarian cancer.
PUBDATE: 19961101
Twenty-two asymptomatic women with rising CA 125 levels after chemotherapy for ovarian cancer were entered into a trial of isotretinoin combined with calcitriol. Tumours were evaluated according to precise criteria based on serial CA 125 levels and by comparing regression slopes of CA 125 before and during therapy. There was no evidence based on CA 125 of any responses or significant change in tumour growth rate.


3. DOCID:23097 SCORE: 0.00353137973944471
DOCNO: 8051769
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prostatectomy
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: H B Heidenberg HB
AUTHOR: J W Moul JW
AUTHOR: F K Mostofi FK
AUTHOR: D G McLeod DG
AFFILIATION: Urology Service, Walter Reed Army Medical Center, Bethesda, Maryland.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Clinically detected carcinoma of the prostate treated by radical prostatectomy in a 29-year-old man.
PUBDATE: 19940901
Prostate cancer is rare in young adults and when clinically detected it has been invariably locally or distantly advanced, undifferentiated and exhibiting aggressive behavior. To our knowledge no previous report documents clinically detected and localized disease amenable to curative surgery in a young adult. We report on a 29-year-old man with clinically detected, moderately differentiated adenocarcinoma of the prostate who was treated by nerve sparing radical retropubic prostatectomy. The patient was disease-free and morbidity-free 30 months after treatment.


4. DOCID:23004 SCORE: 0.00338622062082413
DOCNO: 7609971
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cholecystectomy, Laparoscopic
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: J Sándor J
AUTHOR: M Ihász M
AUTHOR: T Fazekas T
AUTHOR: J Regöly-Mérei J
AUTHOR: J Bátorfi J
AFFILIATION: III. sz. Sebészeti Klinika, Semmelweis Orvostudományi Egyetem, Budapest.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Laparoscopic cholecystectomy and cancer of the gallbladder]
PUBDATE: 19950701
Performing a series of 960 laparoscopic cholecystectomies we have removed 3 unsuspected gallbladder cancers. In one case we have observed the development of trocar site abdominal wall metastasis twice. After resection and reresection of the metastases the patient is symptom-free in the 14th month. During laparoscopic cholecystectomy if there is a suspicion of gallbladder cancer we have to manipulate with special care to avoid rupture of the gallbladder. In doubtful cases frozen section is mandatory. If the malignant process extends over the serosal layer--conversion and radical-extended operation is recommended.


5. DOCID:22807 SCORE: 0.00305553953124535
DOCNO: 8691599
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, Tumor Suppressor
DESCRIPTOR: Oncogenes
QUALIFIER: analysis
AUTHOR: H Kondo H
AUTHOR: A Nobuoka A
AFFILIATION: Division of G1 oncology, National Cancer Center Hospital.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Clinical application of oncogene and antioncogene as a tumor marker]
PUBDATE: 19960601
Since it is generally accepted that neoplasm is developed by accumulation of abnormalities in oncogenes and antioncogenes, these genetic analysis would be useful as new tumor markers. The present clinical applications of genetic analysis of oncogenes are as follows, 1) diagnosis of neoplasm (early detection, differential diagnosis for borderline lesion), 2) speculation of the prognosis of a cancer patient and prediction of chemosensitivity and, 3) establishment of high risk group of cancer. In regard to clinical practice, a medical doctor take care of scientific interpretation of genetic examinations as well as ethical problems.


6. DOCID:21386 SCORE: 0.00296238725399393
DOCNO: 8713631
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: complications
QUALIFIER: drug therapy
AUTHOR: W M O'Neill WM
AFFILIATION: Dept of Palliative Medicine, Bristol Oncology Centre, England.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Middle East journal of anesthesiology.
COUNTRY: LEBANON
TITLE: Cancer pain.
PUBDATE: 19960201
An accurate assessment and where possible a precise diagnosis of the underlying mechanism in necessary for the effective management of pain in cancer. The majority of patients respond to oral analgesics, and the range of drugs required is not vast. Adjuvant analgesic drugs will be needed for the treatment of bone pain, visceral pain and neuropathic pain. For the remaining patients who present with difficult and occasionally intractable pain, a multidisciplinary approach using drug and non-drug measures will usually allow significant relief of symptoms.


7. DOCID:18725 SCORE: 0.00293083048306512
DOCNO: 1585237
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
QUALIFIER: genetics
QUALIFIER: pathology
QUALIFIER: genetics
AUTHOR: F Solé F
AUTHOR: S Woessner S
AUTHOR: A Pérez A
AUTHOR: L Florensa L
AUTHOR: C Besses C
AUTHOR: J Sans Sabrafén J
AFFILIATION: Departamento de Hematología y Oncología, Hospital Central L'Aliança, Barcelona.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Sangre.
COUNTRY: SPAIN
TITLE: [Description of 2 patients with cytogenetically abnormal clones]
PUBDATE: 19920201
We present two patients with two cytogenetically unrelated clones. A patient was diagnosed of refractory anaemia and showed an abnormal clone with trisomy 8 and other clone with 5q-; the other patient, diagnosed as chronic lymphocytic leukaemia showed a clone with an inversion of chromosome 2, inv(2) (p23q12) and the other clone with a 47,XX,+5,t(16;17)(p13;q11),+2ac karyotype. The discussion is focused on the presence of unrelated clones in relation to the monoclonal origin of cancer.


8. DOCID:18812 SCORE: 0.00292472686986987
DOCNO: 1929452
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusion Pumps, Implantable
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: pathology
AUTHOR: M Hoshino M
AUTHOR: Y Koyama Y
AUTHOR: N Satou N
AUTHOR: R Abe R
AFFILIATION: Dept. of Surgery 2, Fukushima Medical College, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Hepatic arterial infusion of farmorubicin (FARM) and 5-fluorouracil (5-FU) in a patient with massive hepatic metastasis from gastric cancer]
PUBDATE: 19911001
A patient with massive hepatic metastasis from gastric cancer was treated with hepatic arterial injection of FARM and 5-FU one month after total gastrectomy. Response rate was 88% at 3 months after arterial infusion therapy. Severe side effects were not seen during treatment. It is suggested that the hepatic arterial infusion of combined FARM and 5-FU is a useful method for treatment of hepatic metastasis of gastric cancer.


9. DOCID:23621 SCORE: 0.00281789015443818
DOCNO: 8903298
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Terminal Care
QUALIFIER: complications
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: S Ramani S
AUTHOR: A B Karnad AB
AFFILIATION: Department of Internal Medicine, Alvin C. York Veterans Affairs Medical Center, Murfreesboro, Tenn, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Southern medical journal.
COUNTRY: UNITED STATES
TITLE: Long-term subcutaneous infusion of midazolam for refractory delirium in terminal breast cancer.
PUBDATE: 19961101
We describe the case of a 56-year-old woman with terminal metastatic breast cancer who had delirium in the form of frightening hallucinations, paranoid delusions, and nightmares resulting in violent agitation. During this period, her bone pains from metastases were well controlled with narcotic analgesics, but her delirium proved refractory to standard doses of drugs such as lorazepam, diazepam, and haloperidol. We report the use of a subcutaneous infusion of midazolam at home and its effectiveness in control of her delirium after other drugs had failed.


10. DOCID:23811 SCORE: 0.00280038538901295
DOCNO: 9246403
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: adverse effects
AUTHOR: J Moni J
AUTHOR: D Nori D
AFFILIATION: Department of Radiation Oncology, New York Hospital, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest surgery clinics of North America.
COUNTRY: UNITED STATES
TITLE: The pitfalls and complications of radiation therapy for esophageal carcinoma.
PUBDATE: 19970801
Radiation therapy is an important part of the management of esophageal cancer. Effective radiation therapy, however, requires careful evaluation of the tumor and the patient, cognizance of the tolerance of normal tissues in the area to the type of chemotherapy or surgical procedure employed, detailed planning, and streamlined delivery. When combining radiation therapy with other modalities of cancer treatment, physicians of both disciplines must be aware of the ability of one modality to potentiate the toxicity of the other. Therapy prescribed with the intention to cure and achieve long-term survival must be planned with consideration for the quality of life of the patient.


11. DOCID:22983 SCORE: 0.00279190824421638
DOCNO: 8965359
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastroscopy
QUALIFIER: methods
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: S Otsuka S
AFFILIATION: First Department of Internal Medicine, Toho University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Endoscopic treatment of early gastric cancer with laser and laserthermia using Nd : YAG laser]
PUBDATE: 19960501
As a therapeutic modality for early gastric cancer, endoscopic laser treatment is indicated in cases where the tumor is an intramucosal carcinoma, the macroscopic type is either I, IIa, or IIc(Ul(-)), and the diameter of the tumor is less than 10 mm. Type I tumors with less than 15 mm diameter and type IIa tumors with less than 20 mm diameter can be included in this indication. Depressed lesions should be treated carefully. Endoscopic laser treatment may be considered for patients who are not candidates for surgery or who refuse surgery.


12. DOCID:17697 SCORE: 0.00277921064186207
DOCNO: 8508382
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: B D Collier BD
AFFILIATION: Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: New radiographic techniques for colorectal cancer.
PUBDATE: 19930601
Before surgical staging and resection, patients with primary colorectal cancer undergo a thorough diagnostic evaluation. The initial imaging study to identify a primary site of disease often is endoscopy, which frequently is supplemented with a double contrast barium enema. Once the presence of colorectal cancer has been established, new radiographic imaging techniques, including computed tomography (CT), magnetic resonance imaging (MRI), and special ultrasound (US) may be used. Clinical questions addressed by these special imaging techniques include detection of liver and lymph metastases and clarification of local extent of disease.


13. DOCID:23953 SCORE: 0.00276178908616192
DOCNO: 7569029
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
AUTHOR: H P Rodemann HP
AUTHOR: M Bamberg M
AFFILIATION: Department of Radiotherapy, Eberhard-Karls-University, Tübingen, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
COUNTRY: IRELAND
TITLE: Cellular basis of radiation-induced fibrosis.
PUBDATE: 19950501
Fibrosis is a common sequela of both cancer treatment by radiotherapy and accidental irradiation and has been described in many tissues including skin, lung, heart and liver. The underlying mechanisms of the radiation-induced fibrosis still remain to be resolved. In the present review we tried to illustrate the basic cellular mechanisms of radiation-induced fibrosis based on the newest findings arising from molecular radiobiology and cell biology. Based on these findings the cellular mechanism of radiation-induced fibrosis can be seen as a multicellular process involving various interacting cell systems in the target organ resulting in the fibrotic phenotype of the fibroblast/fibrocyte cell system.


14. DOCID:21796 SCORE: 0.00271739787435325
DOCNO: 9087202
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: R M Gore RM
AFFILIATION: Department of Radiology, Evanston Hospital-McGaw Medical Center of Northwestern University, Illinois, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Esophageal cancer. Clinical and pathologic features.
PUBDATE: 19970301
Carcinoma of the esophagus remains one of the most lethal of all cancers. In the past, squamous cell carcinomas accounted for over 95% of esophageal malignancies. Over the past two decades, however, there has been a dramatic increase in the incidence of adenocarcinoma arising in columnar cell-lined Barrett's mucosa, accounting for up to 34% of all esophageal cancers in some areas. This article discusses the different demographic, pathologic, therapeutic, and prognostic features of squamous cell and adenocarcinoma of the esophagus.