0. DOCID:19215 SCORE: 0.00427253754095566
DOCNO: 1467774
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: A J Tuyns AJ
AFFILIATION: International Agency for Research on Cancer, Lyon, France.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
COUNTRY: ENGLAND
TITLE: Oesophageal cancer in France and Switzerland: recent time trends.
PUBDATE: 19920401
This paper reports the incidence of oesophageal carcinoma in five cancer registries from France and in a further two from the francophone regions of Switzerland. The cancers are segregated into the two main histological types (squamous cell carcinoma and adenocarcinoma). In Belgium the proportion of adenocarcinomas is much higher than in any of the French registries. A study of time trends shows no clear trend in overall incidence of oesophageal cancer. There is a trend towards an increasing proportion of adenocarcinomas with time, that is most apparent in Doubs, Dijon and Vaud registries.

1. DOCID:18075 SCORE: 0.00424147293313678
DOCNO: 1754083
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrectomy
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: M Ferri M
AUTHOR: M Noia M
AUTHOR: C Manfrè C
AUTHOR: F Mancini F
AUTHOR: A Matrone A
AUTHOR: I Sirovich I
AUTHOR: A Schillaci A
AFFILIATION: V Clinica Chirurgica, Università La Sapienza, Roma.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Surgery by exeresis for gastric carcinoma. An analysis of 165 consecutive cases]
PUBDATE: 19910801
Surgery is still considered the best approach in gastric cancer. The aim of this study was to identify the most important factors involved in the determination of long-term survival. Total and subtotal gastrectomy were analysed. Long-term survival in these patients was strictly correlated with the stage of disease and the infiltration of resection margins. Early diagnosis is confirmed to be the most important factor in the long-term survival of these patients.

2. DOCID:19532 SCORE: 0.00420414061813226
DOCNO: 2307241
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: radiotherapy
AUTHOR: C D Griffith CD
AUTHOR: R Chadderton R
AUTHOR: J B Bourke JB
AFFILIATION: Department of Surgery, Queen's Medical Centre, Nottingham, UK.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Adenocarcinoma of the stomach following radical radiotherapy for testicular cancer.
PUBDATE: 19900201
Two male patients who underwent curative surgery and adjuvant radiotherapy (with further chemotherapy in one) for testicular cancer developed adenocarcinoma of the stomach 5 and 19 years after treatment. The stomach is included in the field of radiotherapy used to treat the para-aortic lymph nodes and this may lead to dysplastic changes in the stomach mucosa which can lead to frank malignancy. Early endoscopy should be offered to patients with dyspeptic symptoms after adjuvant radiotherapy for testicular cancer.

3. DOCID:19516 SCORE: 0.00420413790943774
DOCNO: 2093074
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
AUTHOR: Z Hang Z
AUTHOR: Y Wei Y
PUBTYPE: Journal Article
JOURNALTITLE: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao / [bian ji zhe, Hua xi yi ke da xue xue bao bian wei hui].
COUNTRY: CHINA
TITLE: [Ultrastructural study of stromal elements of lung carcinoma]
PUBDATE: 19900901
We studied the fine features of stromal elements in 33 cases of human lung carcinoma by electron microscopy. Cancer cells showed the damages to the basement membrane and matrix. On the other hand, stromal elements showed changes responding to the invasion of cancer cells. Lymphocytes and macrophages showed the activity of killing cancer cells. Most cell directly contacts the myofibroblast and fibroblast. Matured myofibroblast, early myofibroblast, active fibroblast and resting fibroblast were present near the nest of carcinoma. We discussed the roles and significance of stromal reactions.

4. DOCID:19771 SCORE: 0.00397043915842186
DOCNO: 8459796
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Plants, Toxic
DESCRIPTOR: Population Surveillance
DESCRIPTOR: Tobacco, Smokeless
PUBTYPE: Journal Article
JOURNALTITLE: MMWR. Morbidity and mortality weekly report.
COUNTRY: UNITED STATES
TITLE: Use of smokeless tobacco among adults--United States, 1991.
PUBDATE: 19930401
Consumption of moist snuff and other smokeless tobacco products in the United States almost tripled from 1972 through 1991 (1). Long-term use of smokeless tobacco is associated with nicotine addiction and increased risk of oral cancer (2)--the incidence of which could increase if young persons who currently use smokeless tobacco continue to use these products frequently (1). To monitor trends in the prevalence of use of smokeless tobacco products, CDC's 1991 National Health Interview Survey-Health Promotion and Disease Prevention supplement (NHIS-HPDP) collected information on snuff and chewing tobacco use and smoking from a representative sample of the U.S. civilian, noninstitutionalized population aged > or = 18 years. This report summarizes findings from this survey.

5. DOCID:19238 SCORE: 0.00300973182777291
DOCNO: 1660741
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: M A Goncharskaia MA
AUTHOR: I M Rutkevich IM
AUTHOR: A G Tonevitskiĭ AG
AUTHOR: N F Orel NF
AUTHOR: A V Vasil'ev AV
AUTHOR: N I Perevodchikova NI
AUTHOR: E B Mechetner EB
PUBTYPE: Journal Article
JOURNALTITLE: Biulleten' eksperimental'noĭ biologii i meditsiny.
COUNTRY: USSR
TITLE: [Monoclonal antibodies to human small-cell lung cancer]
PUBDATE: 19910901
Murine monoclonal antibodies to human small cell lung cancer (SCLC) have been developed and partially characterized. Primary hybridoma clones were screened in the indirect immunofluorescence assay (IFA) on alive H417 cells. Then five clones (IgG1, IgG2a, IgG3 and IgM) non-reactive with normal human bone marrow cells and positively reactive with SCLC tumors were selected. The H417.3 antibody is directed against 47-50kD surface antigens of H417 cells. The antibodies are supposed to be applied for the immunodetection of SCLC metastases to bone marrow and immunotoxin preparations.

6. DOCID:19220 SCORE: 0.00296980997595261
DOCNO: 1511159
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: cytology
AUTHOR: A G Knudson AG
AFFILIATION: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Stem cell regulation, tissue ontogeny, and oncogenic events.
PUBDATE: 19920601
The number of necessary oncogenic events is a function of tissue ontogeny. A minimum of two events appears to suffice for certain embryonal tumors, leukemias, and lymphomas for which the target tissues normally show stem cell proliferation. Other tumors, including those featured in the Li-Fraumeni syndrome, arise in target tissues whose stem cells are conditionally stimulated to proliferate, as in response to hormones, and involve more events. The most complex cancers include most carcinomas, which arise in renewal tissues whose stem cells do not normally proliferate. The number of necessary oncogenic events appears to increase with the number of controls on proliferation.

7. DOCID:18002 SCORE: 0.00273963656714728
DOCNO: 1653588
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: pathology
QUALIFIER: radiography
AUTHOR: R H Troupin RH
AUTHOR: S G Orel SG
AFFILIATION: University of Pennsylvania, Philadelphia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in radiology.
COUNTRY: UNITED STATES
TITLE: New insights into mammographic correlations in breast pathology.
PUBDATE: 19910801
Meticulous correlation of mammographic and pathologic findings is essential to improve detection and understanding of the many processes that affect the breast. A review of recent radiologic papers dealing with several breast cancer variants as well as two benign lesions, the radial scar and the breast hamartoma, is presented. Important papers from the pathologic, oncologic, and radiologic literature are reviewed. These papers described the evolving concepts of proliferative breast disease as risk markers, as well as insights into prognostic differences among the histologic subtypes of ductal carcinoma in situ.

8. DOCID:19664 SCORE: 0.0026573481634533
DOCNO: 8445490
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
AUTHOR: S Toikkanen S
AUTHOR: H Joensuu H
AFFILIATION: Department of Pathology, University Central Hospital of Turku, Finland.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of pathology.
COUNTRY: ENGLAND
TITLE: AgNOR counts have no prognostic value in breast cancer.
PUBDATE: 19930201
The prognostic significance of silver-stained nucleolar organizer regions (AgNORs) was retrospectively studied among 230 patients with operable invasive breast cancer from a defined urban population. The number of AgNORs was evaluated from routinely processed paraffin sections by light microscopy at a total magnification of x630. The number of AgNORs had no predictive value on the 8-year survival rate corrected for intercurrent deaths (P = 0.2). A high number of AgNORs (> 2.7, the median value) was not related to any other prognostic variable studied except a low S-phase fraction measured by flow cytometry. AgNOR counting does not appear to be a useful prognostic variable in breast cancer.

9. DOCID:19947 SCORE: 0.00262141494692003
DOCNO: 8504995
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: mortality
AUTHOR: M E O'Brien ME
AUTHOR: J B Schofield JB
AUTHOR: S Tan S
AUTHOR: I Fryatt I
AUTHOR: C Fisher C
AUTHOR: E Wiltshaw E
AFFILIATION: Gynaecological Oncology Unit, Royal Marsden Hospital, London, United Kingdom.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Clear cell epithelial ovarian cancer (mesonephroid): bad prognosis only in early stages.
PUBDATE: 19930501
Clear cell ovarian carcinoma accounts for 4.5% of all cases of ovarian cancer at this center; 43% of patients presented with stage I disease. Stage for stage patients with advanced disease (II-IV) did no worse than other subtypes of epithelial tumors but patients with stage I disease did significantly worse at both 5 (P < 0.05) and 10 years (P < 0.02). Young age (< 60 years), advanced stage, and the presence of vascular invasion are independently poor prognostic factors, while the presence of a predominantly (> 75%) papillary or tubulocystic morphological pattern independently predicts a better prognosis.

10. DOCID:19521 SCORE: 0.00255041128020001
DOCNO: 2269687
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: G Benhamou G
AUTHOR: J P Marmuse JP
AUTHOR: H Johanet H
AUTHOR: J Y Le Goff JY
AUTHOR: F Hecht F
AFFILIATION: Service de Chirurgie Digestive, Hôpital Bichat, Paris.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal de chirurgie.
COUNTRY: FRANCE
TITLE: [Therapeutic diagram in advanced cancers of the esophagus]
PUBDATE: 19901101
Only palliative treatment may be contemplated when advanced oesophageal cancers present with dysphagia. Operability depends on respiratory, hepatic and nutritional status. Resectability may be assessed on the information provided by bronchoscopy, thoracic CT scan and surgical exploration. Advanced resectable oesophageal cancers require oesophagectomy without thoracotomy and radiotherapy. We performed 93 oesophagectomies in 106 advanced oesophageal cancers with a mortality rate of less than 2%. Non resectable advanced oesophageal cancers require bypass procedures. We performed 13 in the 106 cases. Inoperable advanced oesophageal cancers require radiotherapy in the absence of a fistula, laser therapy or an endoprosthesis for dysphagia.

11. DOCID:19290 SCORE: 0.00247273376356362
DOCNO: 8409332
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Expression
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: X Chenivesse X
AUTHOR: D Franco D
AUTHOR: C Bréchot C
AFFILIATION: INSERM U75, C.H.U. Necker, Paris, France.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of hepatology.
COUNTRY: IRELAND
TITLE: MDR1 (multidrug resistance) gene expression in human primary liver cancer and cirrhosis.
PUBDATE: 19930601
MDR1 RNA levels were analysed in patients with hepatocellular carcinoma (HCC), benign liver tumors or cirrhosis. None of the patients with HCC had received chemotherapy. MDR1 RNA levels were increased relative to a normal liver specimen in 15/26 liver cancers, 2/6 benign liver tumors and 0/8 tumor-free cirrhotic livers. MDR1 was also overexpressed in cirrhotic non-tumorous liver tissues of some patients with HCC. The results indicate that the MDR1 gene is overexpressed in liver tumors and some preneoplastic lesions and that might account for the very poor response of primary liver cancers to chemotherapy.

12. DOCID:17956 SCORE: 0.00244232450940331
DOCNO: 2229234
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: isolation & purification
AUTHOR: T M Phillips TM
AUTHOR: J V Babashak JV
AFFILIATION: Immunochemistry Laboratory, George Washington University Medical Center, Washington, DC 20037.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of chromatography.
COUNTRY: NETHERLANDS
TITLE: Isolation of anti-idiotypic antibodies by immunoaffinity chromatography on Affinichrom beads.
PUBDATE: 19900701
Anti-idiotypic antibodies are important regulators of the immune system but they are difficult to isolate and monitor. We have developed a technique for isolating specific auto-anti-idiotypic antibodies by high-performance immunoaffinity chromatography using immobilized autologous anti-tumor antibodies as the affinity ligand. The isolated anti-idiotypes demonstrated the ability to react with the original antitumor antibodies and inhibit their reactivity against autologous tumor cells. This technique can be used to monitor regulatory antibodies in cancer patients receiving immune modulation therapy.

13. DOCID:18127 SCORE: 0.00226347018288386
DOCNO: 1631774
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Dental Implants
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: R F Jacob RF
AUTHOR: G P Reece GP
AUTHOR: T D Taylor TD
AUTHOR: M J Miller MJ
AFFILIATION: M.D. Anderson Cancer Center, Houston, Texas.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Texas dental journal.
COUNTRY: UNITED STATES
TITLE: Mandibular restoration in the cancer patient: microvascular surgery and implant prostheses.
PUBDATE: 19920601
This article deals with state of the art reconstruction and rehabilitation of the head and neck cancer patient who requires mandibular resection. The mandible can be reconstructed by microvascular free tissue transfer of bone and soft tissue from distant body sites. The dental units and missing soft tissue contours can be supported by osseointegrated implants placed in the grafted bone. This article discusses the rationale for patient selection and sequencing of this complex and rewarding rehabilitation.

14. DOCID:18929 SCORE: 0.00215613493096023
DOCNO: 8259855
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: pathology
QUALIFIER: drug therapy
AUTHOR: M Haraguchi M
AUTHOR: S Tsuboi S
AUTHOR: M Fukano M
AUTHOR: A Eguchi A
AUTHOR: Y Iwao Y
AUTHOR: T Furuta T
AFFILIATION: Dept. of Surgery, National Oita Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of early gastric cancer with Virchow's node metastasis, effectively treated by high dose of UFT]
PUBDATE: 19931201
We report a case of early gastric cancer with Virchow's node metastasis. The patient underwent partial gastrectomy and postoperative immunochemotherapy using MMC, 5'-DFUR and PSK, which reduced the Virchow's node. Three years after surgery, we found metastases to the left subclavicular and axillary nodes other than the Virchow's node. Then UFT was administered orally at 600 mg/day, and the metastatic nodes diminished, then vanished. The patient is alive nearly five years after surgery.