0. DOCID:10323 SCORE: 0.00388469591690129
DOCNO: 7108937
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: metabolism
AUTHOR: C Scully C
AUTHOR: T Barkas T
AUTHOR: P Boyle P
AUTHOR: I A McGregor IA
PUBTYPE: Journal Article
JOURNALTITLE: Journal of clinical & laboratory immunology.
COUNTRY: ITALY
TITLE: Circulating immune complexes detected by binding of radiolabelled protein A in patients with oral cancer and oral premalignant lesions.
PUBDATE: 19820601
Circulating immune complexes were determined in 48 patients with oral squamous cell cancer, 17 patients with oral keratosis and 49 controls, using a rapid sensitive assay using a Staphylococcus aureus immunoadsorbent. Concentrations of immune complexes were significantly higher in patients with oral cancer and in patients with oral keratosis than in controls, but the levels in those with oral cancer were not significantly different from those in keratosis. Immune complexes might be responsible for the cell-mediated immune defect in patients with cancer in the head and neck.


1. DOCID:11343 SCORE: 0.00351625467832948
DOCNO: 6544829
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: W B Povah WB
AUTHOR: W Beecroft W
AUTHOR: I Hodson I
AUTHOR: H Yazdi H
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of otolaryngology.
COUNTRY: CANADA
TITLE: Malignant lympho-epithelial lesion--the Manitoba experience.
PUBDATE: 19840601
A retrospective study was carried out utilizing the Records Department of the Health Sciences Centre, St. Boniface General Hospital, and the Manitoba Cancer Treatment and Research Foundation. Seventeen cases of malignant lympho-epithelial lesion were found. The pathology of all cases was reviewed. There were 12 females and five males. Sixteen cases involved the parotid gland and one the submandibular gland. The ages ranged from 17-65 years with the peak incidence in the fourth decade of life. Fifteen of the patients were Eskimos, all residing in the Northwest Territories; two patients were Caucasian. Most patients were treated with a combined modality of surgery with postoperative radiation. The clinical features, pathology, treatment, and final outcome are reviewed.


2. DOCID:10201 SCORE: 0.0033231420024305
DOCNO: 2856957
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: J S Tobias JS
AUTHOR: M H Tattersall MH
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Doing the best for the cancer patient.
PUBDATE: 19850101
An overview is presented of special dilemmas facing the cancer clinician as a result of changes in the nature of cancer care, such as the trends toward multidisciplinary cancer management and toward involving patients in treatment decisions. The desire to introduce experimental treatments may conflict with the welfare of the patient. Informed consent documents are often barely comprehensible and are frequently geared toward legal considerations. A patient needs a reasonable understanding of treatment goals in order to make decisions regarding quantity and quality of survival. Priorities for allocating limited resources must be evaluated, with careful consideration being given to the diverting of funds from unsuccessful therapies to disease prevention.


3. DOCID:11856 SCORE: 0.00323771781394108
DOCNO: 6834843
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: methods
QUALIFIER: diagnostic use
QUALIFIER: diagnostic use
AUTHOR: I L Avis IL
AUTHOR: F P Avis FP
PUBTYPE: Journal Article
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: UNITED STATES
TITLE: A modification of the (75Se) selenomethionine assay for the detection of complement-dependent antibody in human tumor systems.
PUBDATE: 19830401
A modification of Brook's prelabeling (75SE) selenomethionine assay was developed and evaluated for detection of complement-dependent antibody (CDA) in a human tumor system. CDA was indeed detected in some breast cancer patients' sera. To determine whether the assay was reliable and reproducible, xenoantibodies were raised in rabbits by immunization with a human breast cancer line, Sk-Br-3, and tested against that line and five other unrelated human cancer lines. Multiple tests were performed on separate days. It can be concluded from the data that the assay is reliable and reproducible. The assay has wide application in investigating the biologic role of complement-dependent antibody activity in human and experimental animal tumor systems.


4. DOCID:11275 SCORE: 0.00316703377122916
DOCNO: 6150277
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Menopause
QUALIFIER: analogs & derivatives
QUALIFIER: drug therapy
AUTHOR: R C Coombes RC
AUTHOR: P Goss P
AUTHOR: M Dowsett M
AUTHOR: J C Gazet JC
AUTHOR: A Brodie A
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: 4-Hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer.
PUBDATE: 19841201
4-hydroxyandrostenedione, a potent inhibitor of the aromatase (oestrogen synthetase) system, was given to 11 patients with metastatic breast cancer. After a single 500 mg intramuscular injection a sustained reduction of serum oestradiol was observed for at least 1 week in all patients in whom the steroid was measured. 4 patients responded to treatment for periods of up to 4 months, and healing of bone metastases and reduction in size of soft-tissue metastases was evident. The only side-effects were pain at the injection site and hot flushes. 4-hydroxyandrostenedione is a new and specific aromatase inhibitor which shows promise in the treatment of patients with metastatic breast cancer.


5. DOCID:11272 SCORE: 0.00304810156541769
DOCNO: 3964880
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: blood
QUALIFIER: therapy
AUTHOR: S Rössner S
AUTHOR: P O Hedlund PO
AUTHOR: T Jogestrand T
AUTHOR: U Säwe U
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Treatment of prostatic cancer: effects on serum lipoproteins and the cardiovascular system.
PUBDATE: 19850101
We studied 32 patients with prostatic cancer before, and after 1 and 6 months of treatment with orchiectomy, estramustine phosphate or conventional estrogens (polyestradiol phosphate plus ethinyl estradiol). Lipid metabolism was evaluated by lipoprotein analysis and the intravenous fat tolerance test. Effects on the cardiovascular system were studied by exercise electrocardiography, blood volume estimation and thoracic electrical impedance measurement, a sensitive method to detect early signs of fluid retention. Present treatment programs for prostatic cancer seem to result in effects on lipoprotein metabolism that probably are of minor importance for the development of atherosclerotic manifestations. Measurement of thoracic impedance may be of value to detect fluid retention in individual patients.


6. DOCID:10275 SCORE: 0.00292206787718271
DOCNO: 3888336
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: R J Steele RJ
AUTHOR: A P Forrest AP
AUTHOR: T Gibson T
AUTHOR: H J Stewart HJ
AUTHOR: U Chetty U
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of surgery.
COUNTRY: ENGLAND
TITLE: The efficacy of lower axillary sampling in obtaining lymph node status in breast cancer: a controlled randomized trial.
PUBDATE: 19850501
Four hundred and seventeen patients with operable breast cancer treated by simple mastectomy were randomly allocated to have node sampling or total axillary clearance. There was no significant difference in the incidence of node positivity. One hundred and thirty-five patients had node sampling and were randomized at the completion of this procedure to have axillary clearance or to have no further surgery. All node positive patients who went on to have a clearance had positive samples, confirming the accuracy of the sampling technique.


7. DOCID:9621 SCORE: 0.00276108296519914
DOCNO: 6712287
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: P Prior P
AUTHOR: D P Symmons DP
AUTHOR: C F Hawkins CF
AUTHOR: D L Scott DL
AUTHOR: R Brown R
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the rheumatic diseases.
COUNTRY: ENGLAND
TITLE: Cancer morbidity in rheumatoid arthritis.
PUBDATE: 19840401
A consecutive series of 489 patients with rheumatoid arthritis seen at the centre was studied to determine their cancer morbidity. Overall the 36 cancers diagnosed in the series between 1964 and 1981 were not significantly in excess of the expected number, but there was a highly significant excess of tumours of the reticuloendothelial system. The excess was mainly due to 6 observed cases of lymphoma. We conclude that there is a highly significant association between rheumatoid arthritis and the subsequent development of lymphoproliferative malignancy in this series.


8. DOCID:11620 SCORE: 0.00276067397929375
DOCNO: 6609609
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ganglia, Sympathetic
DESCRIPTOR: Nerve Block
DESCRIPTOR: Tomography, X-Ray Computed
AUTHOR: J R Haaga JR
AUTHOR: S H Kori SH
AUTHOR: D W Eastwood DW
AUTHOR: G P Borkowski GP
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: Improved technique for CT-guided celiac ganglia block.
PUBDATE: 19840601
Celiac nerve blocks have been performed without radiologic guidance, but recently several groups have reported computed tomography (CT)-guided techniques. The authors present a new technique of CT-guided celiac nerve block using an 18 gauge Teflon catheter, which permits a test block dose and permanent alcohol block with one procedure. The results of this new technique were very encouraging. Of nine cancer patients who had the test block, seven had good pain relief; these same patients had good pain control with the permanent block. Of six patients with pancreatitis, six had good pain relief from the test block, and three had some long-term relief from the permanent block.


9. DOCID:10719 SCORE: 0.00271129068318279
DOCNO: 6415310
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Antineoplastic Combined Chemotherapy Protocols
QUALIFIER: pharmacology
AUTHOR: M Ogawa M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Current clinical status of new anticancer drugs]
PUBDATE: 19830801
4'-Epiadriamycin demonstrated considerable efficacies in lymphomas, breast cancer and soft part sarcomas with reduced gastrointestinal, hematologic and probably cardiac toxicities. Mitoxantrone appears to be established the clinical role in lymphomas, acute leukemia and breast cancer with mild clinical toxicities. A new analogous compound of cisplatinum CBDCA concluded phase I study and the dose limiting factor was thrombocytopenia. It is of interest that the drug had responders in ovarian cancer during phase I study. The results reported in new anthracyclines; marcellomycin, carminomycin and 4-demethoxydaunorubicin, anthraquinones; ametantrone and bisantrene, new cisplatinums; CHIP, DACCP and TNO-6, and various other drugs including mAMSA, 5'-DFUR, spirogermanium, VP-16-213 and AZQ were reviewed.


10. DOCID:10713 SCORE: 0.00271128920076453
DOCNO: 7092542
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Colonoscopy
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: J S Abrams JS
PUBTYPE: Journal Article
JOURNALTITLE: Archives of surgery (Chicago, Ill. : 1960)
COUNTRY: UNITED STATES
TITLE: A second look at colonoscopy: indications, failures, and costs.
PUBDATE: 19820701
Results of colonoscopy and colonoscopic polypectomy in 599 patients have been reviewed. Added experience has not decreased the number of failures--failure to examine the entire colon, polyps not retrieved for histological examination ("lost polyps"), undetected ("missed") lesions, and false-negative biopsy specimens. The incidence of invasive carcinoma in polyps measuring under 1 cm is less than 1%; polypectomy should be reserved for larger lesions or demonstrated growth of small polyps. Diagnostic colonoscopy in selected patients (those with persistent gross or occult rectal bleeding but normal results from sigmoidoscopic and barium enema studies) demonstrates a causative lesion in greater than 25% and detects a cancer in 5% to 10% of patients.


11. DOCID:10823 SCORE: 0.00265009954645467
DOCNO: 6580489
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: O F Dent OF
AUTHOR: P H Chapuis PH
AUTHOR: J E Payne JE
AUTHOR: J Meyer J
AUTHOR: A M Sutherland AM
AUTHOR: K J Goulston KJ
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Immunodiagnosis of colorectal cancer: clinical evaluation of Tennessee antigen (Tenagen).
PUBDATE: 19831101
Blood samples from 172 consecutive patients undergoing complete colon investigations to exclude colorectal cancer (CC) were examined for levels of Tennessee antigen, i.e., Tenagen (Tg), and carcinoembryonic antigen. Patients included 48 with CC, 34 with adenomatous polyps, 14 with colitis, and 76 with no organic mucosal disease. All patients were investigated by the one clinical and histopathology department. Laboratory estimations were performed blindly. Although there were some statistically significant differences among average values, the degree of overlap among the groups of patients precludes the practical application of Tg in the diagnosis of CC.


12. DOCID:11353 SCORE: 0.00263203515267075
DOCNO: 6513028
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nuclear Warfare
QUALIFIER: epidemiology
AUTHOR: K Iwasaki K
AUTHOR: K Kawamoto K
AUTHOR: I Shimokawa I
AUTHOR: T Matsuo T
AUTHOR: T Ikeda T
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Epidemiological studies on gastric cancer in Nagasaki]
PUBDATE: 19841101
One thousand-four hundred and twenty-four cases of gastric cancer registered at the Nagasaki Tumor Registry between 1973 and 1977 were studied. The incidence of gastric cancer tended to be higher in persons exposed to the atomic bomb within 2.0 km from the hypocenter, especially in young persons, than in non-exposed individuals, but the difference was not statistically significant. Compared with the nonexposed, the corrected relative risk of gastric cancer in persons exposed within 2.0 km from the hypocenter was 1.28 in males and 1.11 in females. In terms of histologic type or location, the incidence of gastric cancer showed no statistically significant difference between the exposed and nonexposed persons.


13. DOCID:11414 SCORE: 0.00263203292861547
DOCNO: 7062528
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: rehabilitation
QUALIFIER: methods
AUTHOR: R F Harvey RF
AUTHOR: H M Jellinek HM
AUTHOR: R V Habeck RV
PUBTYPE: Journal Article
JOURNALTITLE: JAMA : the journal of the American Medical Association.
COUNTRY: UNITED STATES
TITLE: Cancer rehabilitation. An analysis of 36 program approaches.
PUBDATE: 19820401
Information about comprehensive rehabilitation for patients with cancer is limited. Only a few descriptions of existing models are found in the literature. A survey questionnaire concerning the description and operation of cancer rehabilitation programs was developed and mailed to identified programs in 95 facilities throughout the country. Thirty-six facilities responded with data appropriate for analysis of their method of organization, treatment approaches, team composition, program emphasis, evaluation procedures, and program results. A literature and survey analysis provide support for an interdisciplinary team approach for rehabilitation of cancer patients disabled by the disease or its treatment. In addition, the survey shows favorable acceptance and success of cancer rehabilitation programs, especially in community hospital settings.


14. DOCID:10035 SCORE: 0.00253400235074121
DOCNO: 3861885
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Sugiura K
AUTHOR: K Koyama K
AUTHOR: J Katayama J
AUTHOR: K Nonaka K
AUTHOR: Y Yagi Y
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [A report of five cases of multiple cancer with hematologic malignancies]
PUBDATE: 19850701
Five patients with multiple cancers that included hematologic malignancies are described. The incidence of multiple cancers in hematologic malignancies has been 8.8% in the past two and a half years at our hospital. The combinations were: 1) primary bilateral breast cancers and acute monocytic leukemia; 2) breast cancer, malignant lymphoma and gastric cancer; 3) malignant lymphoma and gastric cancer; 4) malignant lymphoma and prostate cancer, and 5) colon cancer and multiple myeloma. Our experience suggests an increasing incidence of multiple cancer in hematologic malignancies.