0. DOCID:19215 SCORE: 0.00427253754095566
DOCNO: 1467774
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: A J Tuyns AJ
AFFILIATION: International Agency for Research on Cancer, Lyon, France.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
COUNTRY: ENGLAND
TITLE: Oesophageal cancer in France and Switzerland: recent time trends.
PUBDATE: 19920401
This paper reports the incidence of oesophageal carcinoma in five cancer registries from France and in a further two from the francophone regions of Switzerland. The cancers are segregated into the two main histological types (squamous cell carcinoma and adenocarcinoma). In Belgium the proportion of adenocarcinomas is much higher than in any of the French registries. A study of time trends shows no clear trend in overall incidence of oesophageal cancer. There is a trend towards an increasing proportion of adenocarcinomas with time, that is most apparent in Doubs, Dijon and Vaud registries.


1. DOCID:18075 SCORE: 0.00424147293313678
DOCNO: 1754083
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrectomy
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: M Ferri M
AUTHOR: M Noia M
AUTHOR: C Manfrè C
AUTHOR: F Mancini F
AUTHOR: A Matrone A
AUTHOR: I Sirovich I
AUTHOR: A Schillaci A
AFFILIATION: V Clinica Chirurgica, Università La Sapienza, Roma.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Surgery by exeresis for gastric carcinoma. An analysis of 165 consecutive cases]
PUBDATE: 19910801
Surgery is still considered the best approach in gastric cancer. The aim of this study was to identify the most important factors involved in the determination of long-term survival. Total and subtotal gastrectomy were analysed. Long-term survival in these patients was strictly correlated with the stage of disease and the infiltration of resection margins. Early diagnosis is confirmed to be the most important factor in the long-term survival of these patients.


2. DOCID:19532 SCORE: 0.00420414061813226
DOCNO: 2307241
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: radiotherapy
AUTHOR: C D Griffith CD
AUTHOR: R Chadderton R
AUTHOR: J B Bourke JB
AFFILIATION: Department of Surgery, Queen's Medical Centre, Nottingham, UK.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
COUNTRY: ENGLAND
TITLE: Adenocarcinoma of the stomach following radical radiotherapy for testicular cancer.
PUBDATE: 19900201
Two male patients who underwent curative surgery and adjuvant radiotherapy (with further chemotherapy in one) for testicular cancer developed adenocarcinoma of the stomach 5 and 19 years after treatment. The stomach is included in the field of radiotherapy used to treat the para-aortic lymph nodes and this may lead to dysplastic changes in the stomach mucosa which can lead to frank malignancy. Early endoscopy should be offered to patients with dyspeptic symptoms after adjuvant radiotherapy for testicular cancer.


3. DOCID:19516 SCORE: 0.00420413790943774
DOCNO: 2093074
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
AUTHOR: Z Hang Z
AUTHOR: Y Wei Y
PUBTYPE: Journal Article
JOURNALTITLE: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao / [bian ji zhe, Hua xi yi ke da xue xue bao bian wei hui].
COUNTRY: CHINA
TITLE: [Ultrastructural study of stromal elements of lung carcinoma]
PUBDATE: 19900901
We studied the fine features of stromal elements in 33 cases of human lung carcinoma by electron microscopy. Cancer cells showed the damages to the basement membrane and matrix. On the other hand, stromal elements showed changes responding to the invasion of cancer cells. Lymphocytes and macrophages showed the activity of killing cancer cells. Most cell directly contacts the myofibroblast and fibroblast. Matured myofibroblast, early myofibroblast, active fibroblast and resting fibroblast were present near the nest of carcinoma. We discussed the roles and significance of stromal reactions.


4. DOCID:19771 SCORE: 0.00397043915842186
DOCNO: 8459796
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Plants, Toxic
DESCRIPTOR: Population Surveillance
DESCRIPTOR: Tobacco, Smokeless
PUBTYPE: Journal Article
JOURNALTITLE: MMWR. Morbidity and mortality weekly report.
COUNTRY: UNITED STATES
TITLE: Use of smokeless tobacco among adults--United States, 1991.
PUBDATE: 19930401
Consumption of moist snuff and other smokeless tobacco products in the United States almost tripled from 1972 through 1991 (1). Long-term use of smokeless tobacco is associated with nicotine addiction and increased risk of oral cancer (2)--the incidence of which could increase if young persons who currently use smokeless tobacco continue to use these products frequently (1). To monitor trends in the prevalence of use of smokeless tobacco products, CDC's 1991 National Health Interview Survey-Health Promotion and Disease Prevention supplement (NHIS-HPDP) collected information on snuff and chewing tobacco use and smoking from a representative sample of the U.S. civilian, noninstitutionalized population aged > or = 18 years. This report summarizes findings from this survey.


5. DOCID:22749 SCORE: 0.00361311674335455
DOCNO: 7867546
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: J A Adwok JA
AFFILIATION: Department of Surgery, College of Health Sciences, University of Nairobi, Kenya.
PUBTYPE: Journal Article
JOURNALTITLE: East African medical journal.
COUNTRY: KENYA
TITLE: Treatment of thyroid cancer.
PUBDATE: 19940801
The management of differentiated thyroid cancer remains controversial. A consecutive series of 234 thyroidectomies done by one surgeon in various Nairobi Hospitals from July 1990 to June 1993 were studied. 18 patients were operated on for thyroid cancer. The procedures ranged from lobectomy to total thyroidectomy. Young adults from 20-40 years of age were mainly affected, with a male/female sex ratio of 8:1. The immediate and subsequent morbidity of the operation of total thyroidectomy, in our opinion, overweighs its advantages of improved disease control. This is particularly so when low socio-economic standards lead to lack of compliance with replacement therapy.


6. DOCID:31483 SCORE: 0.00349820909882922
DOCNO: 16305905
OWNER: NLM
STATUS: In-Process
AUTHOR: Taku Okamoto T
AUTHOR: Daiki Masuya D
AUTHOR: Takashi Nakashima T
AUTHOR: Shinya Ishikawa S
AUTHOR: Yasumichi Yamamoto Y
AUTHOR: Cheng-Long Huang CL
AUTHOR: Hiroyasu Yokomise H
AFFILIATION: Second Department of Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: The Annals of thoracic surgery.
COUNTRY: Netherlands
TITLE: Successful treatment for lung cancer associated with pulmonary sequestration.
PUBDATE: 20051201
We encountered a 69-year-old man with lung adenocarcinoma and pulmonary sequestration. The cancer lesion was located in the left upper lobe, with sequestration of the left lower lobe. Left upper lobectomy was performed after induction chemoradiotherapy, but the sequestered lung lobe was preserved because the preoperative respiratory function was poor. Preservation of the sequestered lung during surgery for lung cancer should be considered in patients who have poor respiratory function and no signs of respiratory infection.


7. DOCID:23090 SCORE: 0.00321378100738071
DOCNO: 7962737
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: etiology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: T T Kirchmann TT
AUTHOR: B R Smoller BR
AUTHOR: J McGuire J
AFFILIATION: Department of Dermatology, Stanford University Medical Center, Palo Alto, CA 94304.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the American Academy of Dermatology.
COUNTRY: UNITED STATES
TITLE: Cutaneous angiosarcoma as a second malignancy in a lymphedematous leg in a Hodgkin's disease survivor.
PUBDATE: 19941101
Angiosarcoma is a rare and highly malignant neoplasm. Cutaneous angiosarcoma not associated with postmastectomy lymphedema is rare. There are only eight reported cases of development of cutaneous angiosarcoma in a lymphedematous extremity in a patient with preexisting malignancy other than breast cancer. This is the first reported case of development of cutaneous angiosarcoma in a lymphedematous extremity in a Hodgkin's disease survivor. A review of cutaneous angiosarcoma associated with lymphedema and a discussion of the pathogenesis of angiosarcoma are included.


8. DOCID:31522 SCORE: 0.00309082467174557
DOCNO: 15280398
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M R Hussein MR
AFFILIATION: Department of Pathology, Assiut University Hospitals, Egypt. mrh17@swissfo.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of clinical pathology.
COUNTRY: England
TITLE: Genetic pathways to melanoma tumorigenesis.
PUBDATE: 20040801
The incidence of cutaneous malignant melanomas is growing faster than that of any other cancer and therefore posing a major heath threat worldwide. In melanocytic skin tumours, the feasibility of correlating a specific pathological stage with a corresponding genetic alteration provides a remarkable opportunity to study the multistep tumorigenesis model. This multistep melanoma tumorigenesis is best described as a continuum of transformation of the melanocytes, melanocytic dysplasia, and melanoma formation. These steps involve genotypic alterations including loss of tumour suppressor genes, microsatellite instability, and alterations of the mismatch repair system. This review seeks to examine melanoma tumorigenesis based on these genetic changes.


9. DOCID:27831 SCORE: 0.00304119400190962
DOCNO: 10222439
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: A Das A
AUTHOR: F H Hochberg FH
AUTHOR: S McNelis S
AFFILIATION: National University of Singapore, Singapore.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of neuro-oncology.
COUNTRY: NETHERLANDS
TITLE: A review of the therapy of paraneoplastic neurologic syndromes.
PUBDATE: 19990101
The therapy of paraneoplastic neurologic syndromes remains unclear and warrants a systematic review of the literature. Reports in English and foreign language literature were abstracted. Data were sorted by the primary paraneoplastic neurologic syndrome, the primary malignancy, and the methods of treatment. Neurologic improvement follows surgical, chemotherapeutic, and radiation treatments. Adjuvant immunosuppressive therapy with steroids, plasmapheresis, or immunoglobulin may help stabilize the progression of neurologic symptoms. Syndromes characterized by inflammation or neurotransmitter production without neuronal loss are most responsive to therapy. While treatment of the underlying cancer with appropriate surgery, chemotherapy, and radiation is recommended, the paraneoplastic syndrome should probably be managed with immunosuppressive therapy.


10. DOCID:31730 SCORE: 0.00303734838743482
DOCNO: 16556007
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Jingwu Xie J
AFFILIATION: University of Texas Medical Branch at Galveston, Sealy Centers for Cancer Cell Biology and Environmental Health, Department of Pharmacology and Toxicology, 301 University Blvd, Galveston, TX 77555-1048, USA. jinxie@utmb.edu.
PUBTYPE: Journal Article
JOURNALTITLE: Future oncology (London)
COUNTRY: England
TITLE: Hedgehog signaling in prostate cancer.
PUBDATE: 20050601
Prostate cancer is the most common malignancy and the second leading cancer-related cause of death in men in the USA. Despite enormous efforts in understanding the molecular basis of prostate cancer, very little progress has been made in prevention and treatment of this often lethal cancer. Recent studies have demonstrated that hedgehog signaling is frequently activated in advanced or metastatic prostate cancers. With small molecule inhibitors available to analyze the hedgehog signaling pathway, a novel rationale for prostate cancer therapy can be devised.


11. DOCID:31727 SCORE: 0.00303734748638192
DOCNO: 16366091
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Rana Sherwani R
AUTHOR: Sabina Khan S
AUTHOR: Nazoora Khan N
AUTHOR: Mohd Kamran M
AUTHOR: Musharraf Husain M
AFFILIATION: Department of Pathology & General Surgery, J.N. Medical College, Aligarh Muslim University, Aligarh. ranasherwani@yahoo.com
PUBTYPE: Journal Article
JOURNALTITLE: Indian journal of pathology & microbiology.
COUNTRY: India
TITLE: Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma.
PUBDATE: 20051001
This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined by quantifying the number of apoptotic bodies per hundred cells (apoptotic index) on haematoxylin and eosin stained histological sections [corrected] A significant correlation was noted between increasing apoptotic indices and increasing Gleason grades within a cancer.


12. DOCID:19238 SCORE: 0.00300973182777291
DOCNO: 1660741
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: M A Goncharskaia MA
AUTHOR: I M Rutkevich IM
AUTHOR: A G Tonevitskiĭ AG
AUTHOR: N F Orel NF
AUTHOR: A V Vasil'ev AV
AUTHOR: N I Perevodchikova NI
AUTHOR: E B Mechetner EB
PUBTYPE: Journal Article
JOURNALTITLE: Biulleten' eksperimental'noĭ biologii i meditsiny.
COUNTRY: USSR
TITLE: [Monoclonal antibodies to human small-cell lung cancer]
PUBDATE: 19910901
Murine monoclonal antibodies to human small cell lung cancer (SCLC) have been developed and partially characterized. Primary hybridoma clones were screened in the indirect immunofluorescence assay (IFA) on alive H417 cells. Then five clones (IgG1, IgG2a, IgG3 and IgM) non-reactive with normal human bone marrow cells and positively reactive with SCLC tumors were selected. The H417.3 antibody is directed against 47-50kD surface antigens of H417 cells. The antibodies are supposed to be applied for the immunodetection of SCLC metastases to bone marrow and immunotoxin preparations.


13. DOCID:19220 SCORE: 0.00296980997595261
DOCNO: 1511159
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: cytology
AUTHOR: A G Knudson AG
AFFILIATION: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Stem cell regulation, tissue ontogeny, and oncogenic events.
PUBDATE: 19920601
The number of necessary oncogenic events is a function of tissue ontogeny. A minimum of two events appears to suffice for certain embryonal tumors, leukemias, and lymphomas for which the target tissues normally show stem cell proliferation. Other tumors, including those featured in the Li-Fraumeni syndrome, arise in target tissues whose stem cells are conditionally stimulated to proliferate, as in response to hormones, and involve more events. The most complex cancers include most carcinomas, which arise in renewal tissues whose stem cells do not normally proliferate. The number of necessary oncogenic events appears to increase with the number of controls on proliferation.


14. DOCID:23072 SCORE: 0.00296581631623704
DOCNO: 9080214
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Interleukin-6
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: T Chard T
AFFILIATION: Department of Reproductive Physiology, St Bartholomew's Hospital Medical College, London, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Human reproduction update.
COUNTRY: ENGLAND
TITLE: Cytokines in implantation.
PUBDATE: 19950701
The process of implantation in the human involves 'invasion' of the maternal endometrium by the trophoblast surrounding the developing blastocyst, in response to which there is a cellular reaction in the endometrium. The overall situation has some features analogous to invasion by a tumour and some which are more characteristic of an inflammatory response. In addition, and also in common with cancer and inflammation, there is a release of biologically active molecules, including cytokines, at and around the implantation site. It is believed that these cytokines may play an important role in the successful establishment of the pregnancy; the evidence for this belief is examined in this review.