0. DOCID:26495 SCORE: 0.00268013360597462
DOCNO: 10700909
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: T Sasaki T
AFFILIATION: Dept. of Chemotherapy, Tokyo Metropolitan Komagome Hospital.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Combination of levofolinate calcium and 5-fluorouracil]
PUBDATE: 20000201
It has been determined that in the combination of Leucovorin (LV) and 5-fluorouracil (5-FU), LV potentiates the cytotoxic effect of 5-FU based on biochemical modulation. Many data suggest that LV/5-FU is a very effective combination, and most clinicians worldwide now regard it as the standard therapy for colorectal cancer. In Japan, clinical examinations of this combination using Levofolinate calcium (I-LV) have shown its effectiveness, and I-LV/5-FU for gastric and colorectal cancer was authorized by the Ministry of Public Welfare in Oct. 1999.

1. DOCID:27996 SCORE: 0.002512246047023
DOCNO: 9679358
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Education, Medical, Continuing
DESCRIPTOR: Health Knowledge, Attitudes, Practice
DESCRIPTOR: Program Evaluation
QUALIFIER: education
QUALIFIER: complications
QUALIFIER: therapy
AUTHOR: C Hines C
AUTHOR: J Bingham J
AUTHOR: N Muirden N
AUTHOR: M Beavis M
AFFILIATION: Peter MacCallum Palliative Care Grants Program. hine0014@baggins.cc.flinders.edu.au
PUBTYPE: Journal Article
JOURNALTITLE: Australian family physician.
COUNTRY: AUSTRALIA
TITLE: Evaluation of a cancer pain education program for general practitioners.
PUBDATE: 19980701
OBJECTIVE: To evaluate a cancer pain education program. METHOD: Participants in the program completed an evaluation form covering various aspects of the program's design. RESULTS: All participants who completed the program were glad that they had done so. The most and least useful aspects are included in the article. Participants were satisfied with the program and eager to participate in similar ones. CONCLUSION: The education program was both successful at improving participants' knowledge of cancer pain management and provided in a manner acceptable to the participants. Ideas for future similar projects are included.

2. DOCID:25764 SCORE: 0.00239209843324997
DOCNO: 10627999
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Electromagnetic Fields
QUALIFIER: radiation effects
AUTHOR: M Babincová M
AUTHOR: P Sourivong P
AUTHOR: D Leszczynska D
AUTHOR: P Babinec P
AFFILIATION: Department of Biophysics and Chemical Physics, Comenius University, Bratislava, Slovakia. babincova@fmph.uniba.sk
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Naturforschung. C, Journal of biosciences.
COUNTRY: GERMANY
TITLE: Activation of hematoporphyrin in alternating magnetic field: possible implications for cancer treatment.
PUBDATE: 19991101
A new mechanism of cell damage by alternating magnetic field with hematoporphyrin is described. C6 glioblastoma cell suspensions were exposed to an alternating magnetic field with frequency 180 kHz up to 60 min in the presence of hematoporphyrin in H2O and in D2O. The results presented suggest that an alternating magnetic field is able to activate hematoporphyrin, and this method may be a basis for cancer treatment.

3. DOCID:30672 SCORE: 0.00226190130579264
DOCNO: 11823691
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: analogs & derivatives
QUALIFIER: chemically induced
AUTHOR: Manuel F Rosado MF
AUTHOR: Daniel H Kett DH
AUTHOR: Roland M H Schein RM
AUTHOR: Francisco J Baraona FJ
AUTHOR: Kasi S Sridhar KS
AFFILIATION: Department of Medicine, Jackson Memorial Hospital, University of Miami School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136-1094, U.S.A.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: United States
TITLE: Severe pulmonary toxicity in a patient treated with gemcitabine.
PUBDATE: 20020201
Gemcitabine is a pyrimidine analog of deoxycytidine with activity against nonhematologic and hematologic malignancies. Its pulmonary toxicity is usually mild and self-limiting. We describe a male patient with lung cancer in whom severe dyspnea and interstitial infiltrates developed after the administration of gemcitabine.

4. DOCID:30666 SCORE: 0.00226190090317772
DOCNO: 12113243
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: therapeutic use
QUALIFIER: diagnosis
QUALIFIER: enzymology
QUALIFIER: analysis
QUALIFIER: antagonists & inhibitors
QUALIFIER: analysis
QUALIFIER: antagonists & inhibitors
AUTHOR: L Austin Doyle LA
AUTHOR: W Edward Highsmith WE
AFFILIATION: Greenebaum Cancer Center, 22 South Greene Street, Baltimore, MD 21201, USA. adoyle@umm.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Expert review of anticancer therapy.
COUNTRY: England
TITLE: Telomerase as a diagnostic and therapeutic target for cancer.
PUBDATE: 20020401
Telomerase is a ribonucleoprotein enzyme responsible for the elongation of telomeres at the ends of chromosomes. It is widely expressed in most cancers, while absent from most normal somatic cells. Telomerase is partially responsible for the cellular immortalization that allows human cancers to progress indefinitely. Due to its widespread occurrence in cancer and its crucial role in the maintenance of the tumor, telomerase is an attractive target for cancer diagnosis and treatment.

5. DOCID:27100 SCORE: 0.00223473772569844
DOCNO: 9601170
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Clinical Competence
DESCRIPTOR: General Practice, Dental
QUALIFIER: etiology
AUTHOR: J Yellowitz J
AUTHOR: A M Horowitz AM
AUTHOR: H S Goodman HS
AUTHOR: M T Canto MT
AUTHOR: N S Farooq NS
AFFILIATION: University of Maryland, Baltimore College of Dental Surgery, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Dental Association (1939)
COUNTRY: UNITED STATES
TITLE: Knowledge, opinions and practices of general dentists regarding oral cancer: a pilot survey.
PUBDATE: 19980501
The authors mailed a pilot survey to 500 randomly selected general dentists. Although most dentists reported their knowledge of oral cancer to be current, their actual knowledge of oral cancer risk factors and signs and symptoms was inconsistent. Conflicting data were also found between their level of knowledge and their provision of oral cancer examinations. Most respondents agreed that patients should undergo an oral cancer examination annually, yet many do not provide this service.

6. DOCID:31904 SCORE: 0.00223004196501014
DOCNO: 14529309
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: therapeutic use
QUALIFIER: methods
AUTHOR: M F Moyers MF
AUTHOR: D W Miller DW
AFFILIATION: Loma Linda University Medical Center, Loma Linda, California 92354, USA. moyers@proton.llumc.edu
PUBTYPE: Journal Article
JOURNALTITLE: Technology in cancer research & treatment.
COUNTRY: United States
TITLE: Range, range modulation, and field radius requirements for proton therapy of prostate cancer.
PUBDATE: 20031001
The Loma Linda University Proton Treatment Facility has treated over 5,000 patients for prostate cancer. Other institutions may find information regarding field size and range requirements for this population of patients useful for designing new proton beamlines. The maximum range, range modulation, and maximum field radius for 240 fields of prostate patients undergoing treatment were sampled and analyzed. Most fields required a range less than 290 mm of water, a modulation width less than or equal to 120 mm, and a radius less than 75 mm.

7. DOCID:30445 SCORE: 0.00218127478313463
DOCNO: 11919208
AUTHOR: F X Bosch FX
AUTHOR: A Lorincz A
AUTHOR: N Muñoz N
AUTHOR: C J L M Meijer CJ
AUTHOR: K V Shah KV
AFFILIATION: Institut Català d'Oncologia, Servei d'Epidemiologia i Registre del Càncer, Gran Via Km 2.7 s/n 08907 L'Hospitalet de Llobregat, 08907 Barcelona, Spain. x.bosch@ico.scs.es
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of clinical pathology.
COUNTRY: England
TITLE: The causal relation between human papillomavirus and cervical cancer.
PUBDATE: 20020401
The causal role of human papillomavirus infections in cervical cancer has been documented beyond reasonable doubt. The association is present in virtually all cervical cancer cases worldwide. It is the right time for medical societies and public health regulators to consider this evidence and to define its preventive and clinical implications. A comprehensive review of key studies and results is presented.

8. DOCID:26827 SCORE: 0.00213548625958297
DOCNO: 11280894
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: S Aoki S
AUTHOR: K Tanaka K
AUTHOR: T Ohori T
AUTHOR: E Nishikawa E
AUTHOR: Y Yamada Y
AUTHOR: N Honda N
AUTHOR: H Fukatsu H
AFFILIATION: Department of Urology, Nagoya Ekisaikai Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: Japan
TITLE: [A case of transitional cell carcinoma of the bladder in a juvenile patient]
PUBDATE: 20010201
A 15-year-old male was referred to our hospital with the chief complaint of gross hematuria. Cystoscopic examination revealed a papillary tumor on the posterior wall. Transurethral resection of the bladder tumor was performed. Histological examination of the excised tumor showed transitional cell carcinoma, grade 1, pTa. Recurrence has not been observed for about 2 years after the operation. We investigated 54 previously reported Japanese cases of bladder cancer before age twenty including the present case.

9. DOCID:29647 SCORE: 0.00212002717432058
DOCNO: 14607373
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: Deborah McCaffrey Boyle DM
AFFILIATION: Banner Good Samaritan Medical Center, 1111 E. McDowell Road, Phoenix, AZ 85006, USA. deborah.boyle@bannerhealth.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Critical reviews in oncology/hematology.
COUNTRY: Ireland
TITLE: Establishing a nursing research agenda in gero-oncology.
PUBDATE: 20031101
Expanding the evidence base of cancer in the elderly is critical to advance the specialty of geriatric oncology nursing. This article will propose topics for nursing investigation relative to prevention and early detection, response to disease and treatment, and psychosocial responses in the elderly at risk for, or having cancer. International considerations for undertaking nursing research with this special population are also described. Current dilemmas requiring investigation and future demographic implications are highlighted.

10. DOCID:31870 SCORE: 0.00209025256479059
DOCNO: 15341784
AUTHOR: Kirsty S Hewitson KS
AUTHOR: Christopher J Schofield CJ
AFFILIATION: Oxford Centre for Molecular Sciences and the Department of Chemistry, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK. kirsty.hewitson@chem.ox.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Drug discovery today.
COUNTRY: England
TITLE: The HIF pathway as a therapeutic target.
PUBDATE: 20040801
Hypoxia-inducible factor (HIF) is an alpha,beta-heterodimeric transcription factor that mediates cellular responses to low oxygen concentration via the transcriptional activation of specific genes involved in both tumorogenesis and angiogenesis. Manipulation of the HIF pathway has potential use for the treatment of ischemic disease and cancer. Unlike HIF-beta, which is constitutively expressed, the levels and activity of the HIF-alpha subunit are regulated by processes involving posttranslational hydroxylation, catalyzed by Fe(II)- and 2-oxoglutarate-dependent oxygenases. This review focuses on the HIF pathway as a therapeutic target.

11. DOCID:31964 SCORE: 0.00209024253532927
DOCNO: 15340416
AUTHOR: Steven A Rosenberg SA
AUTHOR: James C Yang JC
AUTHOR: Nicholas P Restifo NP
AFFILIATION: Surgery Branch of the Center for Cancer Research at the National Cancer Institute, Building 10, Room 2B42, 10 Center Drive, MSC 1502 Bethesda, Maryland 20892-1502, USA. sar@mail.nih.gov
PUBTYPE: Journal Article
JOURNALTITLE: Nature medicine.
COUNTRY: United States
TITLE: Cancer immunotherapy: moving beyond current vaccines.
PUBDATE: 20040901
Great progress has been made in the field of tumor immunology in the past decade, but optimism about the clinical application of currently available cancer vaccine approaches is based more on surrogate endpoints than on clinical tumor regression. In our cancer vaccine trials of 440 patients, the objective response rate was low (2.6%), and comparable to the results obtained by others. We consider here results in cancer vaccine trials and highlight alternate strategies that mediate cancer regression in preclinical and clinical models.

12. DOCID:31972 SCORE: 0.00209023794969601
DOCNO: 15349523
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nephrectomy
QUALIFIER: diagnosis
QUALIFIER: surgery
QUALIFIER: diagnosis
QUALIFIER: surgery
QUALIFIER: diagnosis
QUALIFIER: surgery
AUTHOR: Barry Billings B
AUTHOR: Leon C Hamrick LC
AUTHOR: Anton J Bueschen AJ
AUTHOR: Philip J Kenney PJ
AFFILIATION: Division of Urology, University of Alabama at Birmingham and Saint Vincents Hospital, Birmingham, AL, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: TheScientificWorldJournal [electronic resource].
COUNTRY: United States
TITLE: Coexisting angiomyolipoma and renal cell carcinoma in a kidney of an elderly woman: case report and review of the literature.
PUBDATE: 20040601
Angiomyolipoma is a well described but relatively uncommon benign renal neoplasm composed of varying admixtures of mature adipose tissue, smooth muscle, and thick-walled blood vessels. The incidence of angiomyolipoma is about 0.3% overall. It frequently occurs in patients with tuberous sclerosis. Even more uncommon is the simultaneous occurrence of angiomyolipoma and renal cell cancer in the same kidney in a patient without tuberous sclerosis.

13. DOCID:25866 SCORE: 0.0019980894484584
DOCNO: 11905613
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
AUTHOR: J S Wong JS
AUTHOR: J R Harris JR
AFFILIATION: Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, MA 02115, USA. jwong@lroc.harvard.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The lancet oncology.
COUNTRY: England
TITLE: Importance of local tumour control in breast cancer.
PUBDATE: 20010101
The overall importance of local tumour control in the management of breast cancer, specifically the influence of local control on survival, remains one of the fundamental questions for oncologists. This review addresses the issues surrounding local tumour control, including the evolution of the concept of disease spread, the rationale for local control, the results of studies of radiotherapy after breast-conserving surgery and after mastectomy, and an interpretation of the recent data on post-mastectomy radiotherapy.

14. DOCID:31883 SCORE: 0.00198482386252887
DOCNO: 15519209
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Extracorporeal Membrane Oxygenation
QUALIFIER: methods
QUALIFIER: complications
QUALIFIER: therapy
AUTHOR: Kyung-Hwan Kim KH
AUTHOR: Jin Hyun Kim JH
AUTHOR: Young Whan Kim YW
AFFILIATION: Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea. kkh726@snu.ac.kr
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
COUNTRY: England
TITLE: Use of extracorporeal membrane oxygenation (ECMO) during whole lung lavage in pulmonary alveolar proteinosis associated with lung cancer.
PUBDATE: 20041101
We describe a case of pulmonary alveolar proteinosis in a male adult with lung cancer. To achieve the successful operation of lung cancer, we used percutaneous veno-venous extracorporeal membrane oxygenation (ECMO) during whole lung lavage (WLL) of the contralateral lung. We performed successful WLL under ECMO support.