New Degree Program in Computational Biology

The School of Computer Science and Mellon College of Science have joined forces to establish an exciting new interdisciplinary program leading to a B.S. in Computational Biology. This new degree is a major re-engineering of the current Computational Biology major offered by the department of Biological Sciences (which was the first degree-granting program in Computational Biology in the country). This new degree supplants the old program beginning this year.

The goal of this new degree program is to provide an intensive interdisciplinary education to enable outstanding students to become leaders in identifying and solving tomorrow's biological problems using computational methods. The new program's curriculum is truly interdisciplinary and is designed for students interested in the intersection of Biology and Computer Science.

Applications to the program are invited from current sophomores. Applicants must have completed, or be currently enrolled in: 03-231, Biochemistry I and 15-211, Fundamental Data Structures and Algorithms (for exceptions contact Amy Burkert (MCS students) or Mark Stehlik (SCS students)). Applicants must submit an informal transcript (whiteprint, obtainable from their academic advisor) and an essay of one page that describes why you want to enter the BSCB program and how it fits with your career goals. Completed applications should be submitted to Dr. Amy Burkert in Doherty Hall 1320.

 


What is Computational Biology?

Computational Biology is concerned with solving biological and biomedical problems using mathematical and computational methods.

Computational Biology is recognized as an essential element in modern biological and biomedical research. There have been fundamental changes in biology and medicine, over the past decade, due to spectacular advances in biomedical imaging, genomics, and proteomics. The nature of these changes demands the application of novel theories and advanced computational tools to decipher the implications of these data, and to devise methods of controlling or modifying biological function. Consequently, Computational Biologists must be well trained and grounded in biology, mathematics, and computer science.

 


Example Problems in Computational Biology Research

            Genetics, Genomics, and Proteomics

                        Sequence analysis

                        Evolutionary tree inference

                        Network inference

                        Gene clustering

 

            Biological Modeling and Simulation

                        Predicting responses of biological systems

                        Testing possible mechanisms of molecular action

                        Testing methods for genetic analysis

                        Performing hypothetical experiments

 

            Structural Biology

                        Protein folding and dynamics

                        Structure prediction

                        Structure assignment

                        Structure design

 

            Biological Image Analysis

                        Interpreting physiological data

                        Disease state detection

                        Automated instrument reading

                        Automated interpretation of microscopy data

 

            Computational Neuroscience

                        Genetic basis of neural function

                        Computing with neurons

                        Neural representation of information