"ORF"	"Symbol"	"Alias"	"Curated ortholog in CCC2"	"CCC2 Ortholog supported by other sources"	"Comment"
"YLR131C"	"ACE2"	""	"ace2"	""	"Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate"
"YFL039C"	"ACT1"	"ABY1|END7"	"act1"	""	"Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions"
"YNR044W"	"AGA1"	""	""	""	"Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds"
"YBR070C"	"ALG14"	""	"SPAC5D6.06c"	""	"Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases"
"YKR021W"	"ALY1"	""	"SPBC839.02"	"SPBC2D10.04"	"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm"
"YJL084C"	"ALY2"	""	"SPBC839.02"	"SPBC2D10.04"	"Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p; phosphorylated in vitro by the cyclin-CDK complex, Pcl7p-Pho85p; identified as a potential Cdc28p substrate; mRNA is cell cycle regulated, peaking in M phase"
"YPR034W"	"ARP7"	"SWP61"	""	""	"Actin-related protein involved in transcriptional regulation; subunit of the chromatin remodeling Snf/Swi complex"
"YOR058C"	"ASE1"	"YOR29-09"	"ase1"	""	"Member of a family of microtubule-associated proteins (MAPs) that function at the mitotic spindle midzone; required for spindle elongation; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate"
"YBR200W"	"BEM1"	"SRO1"	"scd2"	""	"Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p"
"YMR055C"	"BUB2"	"PAC7"	"cdc16"	""	"Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage"
"YDR197W"	"CBS2"	"CBP7"	""	""	"Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader"
"YDL102W"	"CDC2"	"HPR6|POL3|TEX1"	""	""	"Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)"
"YGL116W"	"CDC20"	"PAC5"	"slp1"	"srw1"	"Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate"
"YLR274W"	"CDC46"	"BOB1|MCM5"	"mcm5"	""	"Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase"
"YBR202W"	"CDC47"	"MCM7"	""	""	"Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase"
"YPR019W"	"CDC54"	"HCD21|MCM4"	"cdc21"	""	"Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p"
"YJL194W"	"CDC6"	""	"cdc18"	""	"Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p"
"YNL192W"	"CHS1"	"USA4"	"chs2"	""	"Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor"
"YBR038W"	"CHS2"	""	"chs2"	""	"Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis"
"YEL061C"	"CIN8"	"KSL2|SDS15"	"cut7"	""	"Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation"
"YGR108W"	"CLB1"	"SCB1"	"cig2"	"cdc13"	"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome"
"YPR119W"	"CLB2"	""	"cig2"	"cdc13"	"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome"
"YLR210W"	"CLB4"	""	""	"cig1"	"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation"
"YPR120C"	"CLB5"	""	""	"cig1"	"B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase"
"YGR109C"	"CLB6"	""	""	"cig1"	"B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1"
"YML110C"	"COQ5"	"DBI56"	"coq5"	""	"2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; located in mitochondria"
"YKL049C"	"CSE4"	"CSL2"	"cnp1"	"hht1"	"Centromere protein that resembles histones, required for proper kinetochore function; homolog of human CENP-A"
"YMR238W"	"DFG5"	""	"SPBC1198.07c"	"SPBC1198.06c"	"Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p"
"YDL024C"	"DIA3"	""	"pho1"	"SPBC21H7.03c"	"Protein of unknown function, involved in invasive and pseudohyphal growth"
"YNR067C"	"DSE4"	"ENG1"	"eng1"	""	"Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother"
"YBR252W"	"DUT1"	""	"SPAC644.05c"	""	"dUTPase, catalyzes the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication"
"YKL172W"	"EBP2"	""	"ebp2"	""	"Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles"
"YBR078W"	"ECM33"	""	"SPAC1705.03c"	""	"GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; similar to Sps2p and Pst1p"
"YJL196C"	"ELO1"	""	"SPAC1639.01c"	""	"Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids"
"YGL200C"	"EMP24"	"BST2"	"SPCC24B10.17"	""	"Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport"
"YLR056W"	"ERG3"	"PSO6|SYR1"	"SPBC27B12.03c"	""	"C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources"
"YML012W"	"ERV25"	""	"erv25"	""	"Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport"
"YLR300W"	"EXG1"	"BGL1"	"exg1"	""	"Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes"
"YDR261C"	"EXG2"	""	"exg1"	""	"Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor"
"YCR034W"	"FEN1"	"ELO2|GNS1|VBM2"	"SPAC1639.01c"	""	"Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway"
"YPR104C"	"FHL1"	""	""	"fkh2"	"Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing"
"YCR089W"	"FIG2"	""	""	"SPBPJ4664.02"	"Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating"
"YIL131C"	"FKH1"	""	"fkh2"	""	"Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR"
"YNL068C"	"FKH2"	""	"fkh2"	""	"Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR; potential Cdc28p substrate"
"YLR342W"	"FKS1"	"CND1|CWH53|ETG1|GSC1|PBR1"	"bgs2"	"bgs4"	"Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling"
"YPL221W"	"FLC1"	"BOP1|HUF1"	"pkd2"	""	"Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance"
"YAL053W"	"FLC2"	"HUF2"	"pkd2"	""	"Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance"
"YGL139W"	"FLC3"	"HUF3"	"pkd2"	""	"Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER"
"YLR343W"	"GAS2"	""	"SPBC29A10.08"	"SPAC19B12.02c"	"Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p"
"YMR215W"	"GAS3"	""	"SPBC29A10.08"	"SPAC19B12.02c"	"Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall"
"YOL132W"	"GAS4"	""	"SPBC29A10.08"	"SPAC19B12.02c"	"Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall"
"YOL030W"	"GAS5"	""	"SPBC29A10.08"	"SPAC19B12.02c"	"Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall"
"YLL031C"	"GPI13"	"MPC1"	"gpi13"	""	"ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein"
"YCR065W"	"HCM1"	""	""	"fkh2"	"Forkhead transcription factor involved in cell cycle specific transcription of SPC110; dosage-dependent suppressor of calmodulin mutants with specific defects in SPB assembly; involved in telomere maintenance"
"YBL032W"	"HEK2"	"KHD1"	""	"rnc1"	"RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length"
"YBR009C"	"HHF1"	""	"hhf1"	"h4.3"	"One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity"
"YNL030W"	"HHF2"	""	"hhf1"	"h4.3"	"One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity"
"YBR010W"	"HHT1"	"BUR5|SIN2"	"hht1"	"h3.3"	"One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation"
"YNL031C"	"HHT2"	""	"hht1"	"h3.3"	"One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation"
"YMR032W"	"HOF1"	"CYK2"	"imp2"	"cdc15"	"Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p"
"YOR025W"	"HST3"	""	""	""	"Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"
"YDR191W"	"HST4"	""	""	""	"Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"
"YDR225W"	"HTA1"	"H2A1|SPT11"	"hta2"	"hta1"	"One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p "
"YBL003C"	"HTA2"	"H2A2"	"hta2"	"hta1"	"One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p "
"YDR224C"	"HTB1"	"SPT12"	"htb1"	""	"One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation "
"YBL002W"	"HTB2"	""	"htb1"	""	"One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation"
"YOL012C"	"HTZ1"	"HTA3"	"pht1"	""	"Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin"
"YPL242C"	"IQG1"	"CYK1"	"rng2"	""	"Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family"
"YPR141C"	"KAR3"	"OSR11"	"klp2"	""	"Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate"
"YGR238C"	"KEL2"	""	"tea1"	"tea3"	"Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate"
"YBL063W"	"KIP1"	"CIN9"	"cut7"	""	"Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p "
"YPL155C"	"KIP2"	""	""	"klp5"	"Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle"
"YGL216W"	"KIP3"	""	"klp6"	"klp5"	"Kinesin-related motor protein involved in mitotic spindle positioning "
"YKL008C"	"LAC1"	"DGT1"	"SPBC3E7.15c"	""	"Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p"
"YDL056W"	"MBP1"	""	"res2"	"res1"	"Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes"
"YBL023C"	"MCM2"	""	""	""	"Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"
"YEL032W"	"MCM3"	""	"mcm3"	""	"Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"
"YGL201C"	"MCM6"	""	"mcm6"	""	"Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex"
"YPR138C"	"MEP3"	""	"SPCPB1C11.01"	""	"Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease"
"YIL106W"	"MOB1"	""	"mob1"	""	"Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex"
"YOL112W"	"MSB4"	""	""	""	"GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization"
"YOL090W"	"MSH2"	"PMS5"	""	""	"Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP"
"YDR097C"	"MSH6"	"PMS3"	"msh6"	""	"Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p"
"YHR086W"	"NAM8"	"MRE2|MUD15"	"csx1"	"SPBC23E6.01c"	"RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA"
"YJL116C"	"NCA3"	""	"psu1"	""	"Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family"
"YOR373W"	"NUD1"	""	"cdc11"	""	"Component of the spindle pole body outer plaque, required for exit from mitosis"
"YDR150W"	"NUM1"	"PAC12"	""	""	"Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex"
"YML065W"	"ORC1"	""	""	""	"Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p"
"YBR233W"	"PBP2"	"HEK1"	"rnc1"	""	"RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length"
"YMR076C"	"PDS5"	""	"pds5"	""	"Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold"
"YKL127W"	"PGM1"	""	"SPBC32F12.10"	""	"Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism"
"YAR071W"	"PHO11"	""	"pho1"	"SPBC21H7.03c"	"One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2"
"YHR215W"	"PHO12"	"PHO10"	"pho1"	"SPBC21H7.03c"	"One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation"
"YBR092C"	"PHO3"	""	"pho1"	"SPBC21H7.03c"	"Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin"
"YBR093C"	"PHO5"	""	"pho1"	"SPBC21H7.03c"	"Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2"
"YDR481C"	"PHO8"	""	"SPBC14F5.13c"	""	"Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides"
"YML061C"	"PIF1"	"TST1"	"pfh1"	""	"DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA"
"YMR008C"	"PLB1"	""	"SPBC1348.10c"	"SPAC1A6.03c"	"Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol"
"YOL011W"	"PLB3"	""	"SPBC1348.10c"	"SPAC1A6.03c"	"Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro"
"YNL102W"	"POL1"	"CDC17|CRT5|HPR3"	"pol1"	""	"Catalytic subunit of the DNA polymerase alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis"
"YNL262W"	"POL2"	"DUN2"	"cdc20"	""	"Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair"
"YEL060C"	"PRB1"	"CVT1"	"isp6"	""	"Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation"
"YKL045W"	"PRI2"	""	"spp2"	""	"Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair"
"YDR055W"	"PST1"	""	"SPAC1705.03c"	""	"Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1"
"YER095W"	"RAD51"	"MUT5"	"rhp51"	""	"Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein"
"YAR007C"	"RFA1"	"BUF2|FUN3|RPA1"	"ssb1"	""	"Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"
"YOR127W"	"RGA1"	"DBM1|THE1"	""	""	"GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"
"YDL138W"	"RGT2"	""	""	"ght3"	"Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes"
"YPR165W"	"RHO1"	""	""	"cdc42"	"GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)"
"YPL208W"	"RKM1"	""	"SPBC1709.13c"	""	"SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)"
"YER070W"	"RNR1"	"CRT7|RIR1|SDS12"	"cdc22"	""	"Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits"
"YIL066C"	"RNR3"	"DIN1|RIR3"	"cdc22"	""	"Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits"
"YOR018W"	"ROD1"	""	"SPCC584.15c"	"SPAC31A2.12"	"Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase"
"YFR022W"	"ROG3"	""	"SPCC584.15c"	"SPAC31A2.12"	"Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant"
"YHR031C"	"RRM3"	"RTT104"	"pfh1"	""	"DNA helicase involved in rDNA replication and Ty1 transposition; structurally and functionally related to Pif1p"
"YGR152C"	"RSR1"	"BUD1"	""	""	"GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases"
"YLR180W"	"SAM1"	"ETH10"	"sam1"	""	"S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)"
"YDR502C"	"SAM2"	"ETH2"	"sam1"	""	"S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)"
"YDR077W"	"SED1"	""	""	""	"Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites"
"YIL123W"	"SIM1"	""	"psu1"	""	"Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated"
"YOR307C"	"SLY41"	""	"SPBC83.11"	""	"Protein involved in ER-to-Golgi transport"
"YFL008W"	"SMC1"	"CHL10"	""	""	"Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure"
"YJL074C"	"SMC3"	""	"psm3"	""	"Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member"
"YLR383W"	"SMC6"	"RHC18"	""	""	"Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18"
"YHR050W"	"SMF2"	""	"SPAC27F1.08"	""	"Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins"
"YLR034C"	"SMF3"	""	"SPAC27F1.08"	""	"Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins"
"YLL021W"	"SPA2"	"FUS6|PEA1"	"SPAC3G9.05"	""	"Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate"
"YLR313C"	"SPH1"	""	"SPAC3G9.05"	""	"Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p"
"YOR190W"	"SPR1"	"SSG1"	"exg1"	""	"Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance"
"YML034W"	"SRC1"	"YML033W"	"SPAC14C4.05c"	""	"Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery"
"YMR183C"	"SSO2"	""	"psy1"	""	"Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p"
"YPL092W"	"SSU1"	"LPG16"	"SPBPB10D8.04c"	""	"Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein"
"YLR045C"	"STU2"	""	"dis1"	"alp14"	"Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p"
"YLR372W"	"SUR4"	"APA1|ELO3|SRE1|VBM1"	"SPAC1639.01c"	""	"Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis"
"YJL187C"	"SWE1"	"WEE1"	"mik1"	""	"Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate"
"YER111C"	"SWI4"	"ART1"	"res1"	"res2"	"DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair"
"YDR146C"	"SWI5"	""	""	""	"Transcription factor that activates transcription of genes expressed in G1 phase and at the G1/M boundary; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase"
"YLR182W"	"SWI6"	"PSL8|SDS11"	"cdc10"	"res1"	"Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate"
"YPL128C"	"TBF1"	"LPI16"	"trf1"	""	"Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation"
"YIL144W"	"TID3"	"HEC1|NDC80"	"ndc80"	""	"Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering"
"YLR136C"	"TIS11"	"CTH2"	""	"zfs1"	"mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis"
"YBR162C"	"TOS1"	""	"SPBP23A10.11c"	""	"Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C"
"YFL037W"	"TUB2"	"ARM10|SHE8"	"nda3"	""	"Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules"
"YLR212C"	"TUB4"	""	""	""	"Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body"
"YCR084C"	"TUP1"	"AAR1|AER2|AMM1|CRT4|CYC9|FLK1|ROX4|SFL2|UMR7"	""	""	"General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
"YKL035W"	"UGP1"	""	"SPCC1322.04"	""	"UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p"
"YDR400W"	"URH1"	""	"SPAC17G8.02"	"SPBC1683.06c"	"Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in recycling pyrimidine deoxy- and ribonucleosides via the pyrimidine salvage pathway"
"YKR042W"	"UTH1"	""	"psu1"	""	"Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death"
"YBL004W"	"UTP20"	""	"SPBC56F2.04"	""	"Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA"
"YGL255W"	"ZRT1"	""	"SPBC16D10.06"	""	"High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor"
"YNL313C"	NA	NA	"SPAC19B12.01"	""	NA
"YOR246C"	NA	NA	"SPCC736.13"	""	NA
"YMR244W"	NA	NA	"adg3"	""	NA
"YPL247C"	NA	NA	"SPBC17D11.08"	""	NA