WORDS
drug
receptor
dopamine
brain
receptors
effects
drugs
cocaine
effect
behavior
pain
abuse
mice
behavioral
rats
substance
animals
activity
addiction
pkc
serotonin
administration
neurons
system
treatment
university
stress
morphine
heroin
function
dependence
alcohol
agonist
responses
fig
neurotransmitter
induced
withdrawal
role
transporter
mediated
increased
arrestin
like
dopaminergic
usa
specific
response
institute
rat
research
dependent
adrenergic
actions
medicine
doses
central
thc
antagonist
results
expression
exposure
dose
symptoms
antagonists
center
opioid
binding
psychiatry
nervous
increase
agonists
studies
release
profilin
concentrations
self
medical
sensitivity
addictive
changes
department
systems
action
brains
chronic
marijuana
observed
animal
nucleus
opiate
evidence
injection
enhanced
mechanisms
inhibition
levels
known
school
repeated
RELATED TOPICS
synaptic neurons glutamate nmda receptors
insulin glucose mice diabetes hormone
cells endothelial blood factor growth
ras gtp protein camp atp
disease patients drug new clinical
drug receptor dopamine brain receptors
RELATED DOCUMENTS
"Opposite Modulation of Cocaine-Seeking Behavior by D$_1$-and D$_2$-Like Dopamine Receptor Agonists" (1996)
"Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common $\mu_1$ Opioid Receptor Mechanism" (1997)
"Drug Abuse: Hedonic Homeostatic Dysregulation" (1997)
"Modulation of Cocaine Self-Administration in the Rat Through D-3 Dopamine Receptors" (1993)
"Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal" (1997)
"Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide" (1996)
"Molecular and Cellular Basis of Addiction" (1997)
"Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point" (1998)
"Regulation of Cocaine Reward by CREB" (1998)
"Enhanced Morphine Analgesia in Mice Lacking $\beta$-Arrestin 2" (1999)
"Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801" (1991)
"Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB$_1$ Receptor Knockout Mice" (1999)
"Cocaine Addiction: Psychology and Neurophysiology" (1991)
"Enhanced Cortical Dopamine Output and Antipsychotic-Like Effects of Raclopride by $\alpha_2$ Adrenoceptor Blockade" (1999)
"Sensitization to Morphine Induced by Viral-Mediated Gene Transfer" (1997)
"Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors" (1998)
"Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity" (1999)
"Marijuana: Harder Than Thought?" (1997)
"Common Neural Substrates for the Addictive Properties of Nicotine and Cocaine" (1997)
"Phosphorylation and Sequestration of Serotonin Transporters Differentially Modulated by Psychostimulants" (1999)
"Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB" (1996)
"Shaking Out the Cause of Addiction" (1996)
"A Range of Research-Based Pharmacotherapies for Addiction" (1997)
"OPC-21268, an Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist" (1991)
"Enhanced Myocardial Function in Transgenic Mice Overexpressing the $\beta_2$-Adrenergic Receptor" (1994)
"Reward for Persistence in Substance P Research" (1998)
"Ice: A New Dosage Form of an Old Drug" (1990)
"Cholecystokinin Antianalgesia: Safety Cues Abolish Morphine Analgesia" (1992)
"DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission" (1998)
"Rat Study Sheds Light on Cocaine Craving" (1996)
"Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors" (1998)
"D$_1$ and D$_2$ Dopamine Receptor-Regulated Gene Expression of Striatonigral and Striatopallidal Neurons" (1990)
"Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK$_1$) Receptor Antagonist" (1991)
"New Clues to Brain Dopamine Control, Cocaine Addiction" (1996)
"Social Status Sculpts Activity of Crayfish Neurons" (1996)
"Getting the Brain's Attention" (1997)
"Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics" (1999)
"The Effect of Social Experience on Serotonergic Modulation of the Escape Circuit of Crayfish" (1996)
"Fyn-Kinase as a Determinant of Ethanol Sensitivity: Relation to NMDA- Receptor Function" (1997)
"Requirement of Circadian Genes for Cocaine Sensitization in Drosophila" (1999)
"Cardiac Function in Mice Overexpressing the $\beta$-Adrenergic Receptor Kinase or a $\beta$ARK Inhibitor" (1995)
"Role of $\beta$-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization" (1996)
"Agmatine: An Endogenous Clonidine-Displacing Substance in the Brain" (1994)
"Convergent Pathways for Steroid Hormone-and Neurotransmitter-Induced Rat Sexual Behavior" (1994)
"Teaching the Brain to Take Drugs" (1998)
"Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition" (1997)
"Will New Dopamine Receptors Offer a Key to Schizophrenia?" (1994)
"Enhanced Aggressive Behavior in Mice Lacking 5-HT$_{1B}$ Receptor" (1994)
"Cloning of a Delta Opioid Receptor by Functional Expression" (1992)
"$\beta$-Arrestin: A Protein That Regulates $\beta$-Adrenergic Receptor Function" (1990)
"Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats" (1998)
"The Actin-Binding Protein Profilin Binds to PIP$_2$ and Inhibits Its Hydrolysis by Phospholipase C" (1990)
"Role of $\beta\gamma$ Subunits of G Proteins in Targeting the $\beta$-Adrenergic Receptor Kinase to Membrane-Bound Receptors" (1992)
"Drug Abuse Policy" (1991)
"Psychoactive Drug Use in Evolutionary Perspective" (1997)
"Antibody-Catalyzed Degradation of Cocaine" (1993)
"Dopamine's Role" (1997)
"Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides" (1993)
"A Potent Nonpeptide Antagonist of the Substance P (NK$_1$) Receptor" (1991)
"Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor" (1992)
"Amelioration of Vascular Dysfunctions in Diabetic Rats by an Oral PKC $\beta$ Inhibitor" (1996)
"Phencyclidine, Dizocilpine, and Cerebrocortical Neurons" (1990)
"Enzyme Linked to Alcohol Sensitivity in Mice" (1997)
"Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter" (1991)
"Addiction is a Brain Disease, and it Matters" (1997)
"Central Hypotensive Effects of the $\alpha_{2a}$-Adrenergic Receptor Subtype" (1996)
"The Biology of Being Frazzled" (1998)
"No Pain, No Gain?" (1990)
"Genetic Differences in the Ethanol Sensitivity of GABA$_A$ Receptors Expressed in Xenopus Oocytes" (1990)
"Hyperalgesia Mediated by Spinal Glutamate or Substance P Receptor Blocked by Spinal Cyclooxygenase Inhibition" (1992)
"Thinking About Prozac" (1994)
"Genetic Animal Models of Alcohol and Drug Abuse" (1994)
"Behavioral Effects of Progesterone Associated with Rapid Modulation of Oxytocin Receptors" (1990)
"Pot, Heroin Unlock New Areas for Neuroscience" (1992)
"Cloning of a Serotonin Transporter Affected by Antidepressants" (1991)
"$\beta$-Adrenergic Receptor Kinase-2 and $\beta$-Arrestin-2 as Mediators of Odorant-Induced Desensitization" (1993)
"Long-Term Behavioral Recovery in Parkinsonian Rats by an HSV Vector Expressing Tyrosine Hydroxylase" (1994)
"A Corticosteroid Receptor in Neuronal Membranes" (1991)
"Preserved Acute Pain and Reduced Neuropathic Pain in Mice Lacking PKC $\gamma$" (1997)
"The Drug Dilemma: Manipulating the Demand" (1990)
"An All D-Amino Acid Opioid Peptide with Central Analgesic Activity from a Combinatorial Library" (1994)
"Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA" (1991)
"Behavioral Effects and Gene Delivery in a Rat Model of Parkinson's Disease" (1995)
"Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells" (1990)
"Modulation of Serotonin-Controlled Behaviors by G$_o$ in Caenorhabditis elegans" (1995)
"Psychobiology and Biopsychology" (1996)
"Controls for Lesions of the Nigrostriatal Dopamine System" (1991)
"Transmission of Chronic Nociception by Spinal Neurons Expressing the Substance P Receptor" (1999)
"Tourette Syndrome: Prediction of Phenotypic Variation in Monozygotic Twins by Caudate Nucleus D2 Receptor Binding" (1996)
"New Nonopioid Painkiller Shows Promise in Animal Tests" (1998)
"Marijuana Receptor Gene Cloned" (1990)
"Early Fast Track" (1991)
"Good Pain, Bad Pain" (1997)
"The Heroin Prescribing Debate: Integrating Science and Politics" (1999)
"Inhibition of Myosin Light Chain Kinase by p21-Activated Kinase" (1999)
"Stimulation of Phospholipase C-$\gamma$l Membrane Association by Epidermal Growth Factor" (1990)
"Marijuana Addiction" (1997)
"Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus" (1990)
"Pain-Killer Genes" (1999)
"Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C" (1992)