WORDS
rna
dna
site
structure
polymerase
two
base
splicing
fig
binding
sequence
transcription
strand
trna
mrna
specific
protein
complex
cleavage
rnas
sites
intron
introns
splice
pre
reaction
catalytic
template
sequences
three
nucleotides
loop
group
helix
end
synthesis
enzyme
substrate
activity
domain
active
nuclear
vitro
form
single
recognition
amino
conserved
rrna
ribozyme
coli
molecular
molecules
stranded
university
department
nucleotide
ribosomal
elongation
mechanism
exon
formation
acid
structures
small
interactions
region
pairs
position
first
pair
ribosome
promoter
shown
structural
transfer
model
complexes
step
crystal
core
editing
gene
residues
reactions
molecule
factors
rnap
regions
subunit
rnase
science
containing
major
function
groove
required
vol
enzymes
interaction
RELATED TOPICS
gene dna mutations mutation mutant
structure binding peptide structural bound
dna cancer repair risk exposure
protein proteins binding domain membrane
dna replication cell chromosome chromosomes
protein sequence amino cdna fig
rna dna site structure polymerase
sequence dna genome sequences genes
enzyme enzymes iron protein electron
RELATED DOCUMENTS
"Two Domains of Yeast U6 Small Nuclear RNA Required for Both Steps of Nuclear Precursor Messenger RNA Splicing" (1990)
"External Guide Sequences for an RNA Enzyme" (1990)
"Functional Transcription Elongation Complexes from Synthetic RNA-DNA Bubble Duplexes" (1992)
"Recognition of the Codon-Anticodon Helix by Ribosomal RNA" (1999)
"The U5 and U6 Small Nuclear RNAs as Active Site Components of the Spliceosome" (1993)
"Splice-Site Selection and Decoding: Are They Related?" (1993)
"Minor Groove Recognition of the Conserved G.U Pair at the Tetrahymena Ribozyme Reaction Site" (1995)
"Conservation of Substrate Recognition Mechanisms by tRNA Splicing Endonucleases" (1998)
"Role of U6 snRNA in 5' Splice Site Selection" (1993)
"Structure of a Transcribing T7 RNA Polymerase Initiation Complex" (1999)
"Splicing Takes a Holliday" (1992)
"Joining the Two Domains of a Group I Ribozyme to Form the Catalytic Core" (1997)
"Bimolecular Exon Ligation by the Human Spliceosome" (1997)
"A Multisubunit Ribozyme That Is a Catalyst of and Template for Complementary Strand RNA Synthesis" (1991)
"Interactions of Small Nuclear RNA's with Precursor Messenger RNA During in Vitro Splicing" (1992)
"Participation of the Intron in the Reaction Catalyzed by the Xenopus tRNA Splicing Endonuclease" (1992)
"Group II Intron RNA Catalysis of Progressive Nucleotide Insertion: A Model for RNA Editing" (1993)
"Site-Specific Modification of Pre-mRNA: The 2'-Hydroxyl Groups at the Splice Sites" (1992)
"Group I Intron Self-Splicing with Adenosine: Evidence for a Single Nucleoside-Binding Site" (1991)
"Highly Diverged U4 and U6 Small Nuclear RNAs Required for Splicing Rare AT-AC Introns" (1996)
"Second Structural Motif for Recognition of DNA by Oligonucleotide-Directed Triple-Helix Formation" (1991)
"Ribosome-Catalyzed Peptide-Bond Formation with an A-Site Substrate Covalently Linked to 23S Ribosomal RNA" (1998)
"Recognition of tRNA Precursors: A Role for the Intron" (1992)
"Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA" (1993)
"Mechanism of Intrinsic Transcription Termination and Antitermination" (1999)
"Pseudo-Half-Knot Formation with RNA" (1992)
"Circularly Permuted tRNAs as Specific Photoaffinity Probes of Ribonuclease P RNA Structure" (1993)
"Footprinting the Sites of Interaction of Antibiotics with Catalytic Group I Intron RNA" (1993)
"Major Groove Accessibility of RNA" (1993)
"Promoter Recognition as Measured by Binding of Polymerase to Nontemplate Strand Oligonucleotide" (1997)
"Crystal Structure and Evolution of a Transfer RNA Splicing Enzyme" (1998)
"Movement of the Guide Sequence During RNA Catalysis by a Group I Ribozyme" (1993)
"Mapping the Inside of the Ribosome with an RNA Helical Ruler" (1997)
"RNA Editing: A Mechanism for gRNA-Specified Uridylate Insertion into Precursor mRNA" (1996)
"Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases" (1993)
"Control of Alternative Splicing by the Differential Binding of U1 Small Nuclear Ribonucleoprotein Particle" (1991)
"RNA Tertiary Structure Mediation by Adenosine Platforms" (1996)
"Spatial Organization of Transcription Elongation Complex in Escherichia coli" (1998)
"Catalytic Site Components Common to Both Splicing Steps of a Group II Intron" (1994)
"Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing" (1996)
"Requirement of U12 snRNA for In vivo Splicing of a Minor Class of Eukaryotic Nuclear Pre-mRNA Introns" (1996)
"Bent Helix Formation Between RNA Hairpins with Complementary Loops" (1995)
"The 2.9 $\overset{\circ}{\mathrm A}$ Crystal Structure of T. thermophilus Seryl-tRNA Synthetase Complexed with tRNA$^{Ser}$" (1994)
"Catalytic Activity of an RNA Domain Derived from the U6-U4 RNA Complex" (1994)
"Guides to the Heart of the Spliceosome" (1993)
"V(D)J Recombination and Transposition: Closer Than Expected" (1996)
"A Conformational Switch in Escherichia coli 16S Ribosomal RNA During Decoding of Messenger RNA" (1997)
"RNA Editing: Transfer of Genetic Information from gRNA to Precursor mRNA in Vitro" (1994)
"A U1/U4/U5 snRNP Complex Induced by a 2'-O-Methyl-Oligoribonucleotide Complementary to U5 snRNA" (1996)
"Five Easy Pieces" (1991)
"AT-AC Introns: An ATtACk on Dogma" (1996)
"Insights into Editing from an Ile-tRNA Synthetase Structure with tRNA$^{Ile}$ and Mupirocin" (1999)
"Crystal Structure of a Conserved Ribosomal Protein-RNA Complex" (1999)
"Identification of Bases in 16S rRNA Essential for tRNA Binding at the 30S Ribosomal P Site" (1995)
"Discrete Determinants in Transfer RNA for Editing and Aminoacylation" (1997)
"Interaction of U6 snRNA with a Sequence Required for Function of the Nematode SL RNA in Trans-Splicing" (1992)
"Determination of Intrinsic Transcription Termination Efficiency by RNA Polymerase Elongation Rate" (1994)
"Specificity for Aminoacylation of an RNA Helix: An Unpaired, Exocyclic Amino Group in the Minor Groove" (1991)
"Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase" (1992)
"The Shrewd Grasp of RNA Polymerase" (1996)
"A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerase" (1994)
"Enzyme Structure with Two Catalytic Sites for Double-Sieve Selection of Substrate" (1998)
"Mechanisms of Alternative Pre-mRNA Splicing" (1991)
"Selection of a Ribozyme That Functions as a Superior Template in a Self-Copying Reaction" (1992)
"RNA Polymerase Marching Backward" (1993)
"Identity Elements for Specific Aminoacylation of Yeast tRNA$^{Asp}$ by Cognate Aspartyl-tRNA Synthetase" (1991)
"Change of a Catalytic Reaction Carried Out by a DNA Replication Protein" (1996)
"Aminoacyl Esterase Activity of the Tetrahymena Ribozyme" (1992)
"A Freeze-Frame View of Eukaryotic Transcription During Elongation and Capping of Nascent mRNA" (1992)
"Messenger RNA Splicing in Yeast: Clues to why the Spliceosome is a Ribonucleoprotein" (1991)
"A Parallel Spliceosome" (1996)
"Functional Evidence for Indirect Recognition of G.U in tRNA$^{Ala}$ by Alanyl-tRNA Synthetase" (1996)
"Kinetic Characterization of Ribonuclease-Resistant 2'-Modified Hammerhead Ribozymes" (1991)
"Mutations in U6 snRNA that Alter Splice Site Specificity: Implications for the Active Site" (1993)
"Discontinuous Mechanisms of Transcription Elongation" (1994)
"Mutational Isolation of a Sieve for Editing in a Transfer RNA Synthetase" (1994)
"Assembly of a Ribonucleoprotein Catalyst by Tertiary Structure Capture" (1996)
"Ribosomal RNA Precursor Processing by a Eukaryotic U3 Small Nucleolar RNA-Like Molecule in an Archaeon" (1995)
"Structure of the A Site of Escherichia coli 16S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic" (1996)
"A Preorganized Active Site in the Crystal Structure of the Tetrahymena Ribozyme" (1998)
"Coaxially Stacked RNA Helices in the Catalytic Center of the Tetrahymena Ribozyme" (1994)
"Fragments of the HIV-1 Tat Protein Specifically Bind TAR RNA" (1990)
"Switching Recognition of Two tRNA Synthetases with an Amino Acid Swap in a Designed Peptide" (1995)
"New Horizons for RNA Catalysis" (1992)
"RNA Editing-A Novel Genetic Phenomenon?" (1990)
"An Adenosine Deaminase That Generates Inosine at the Wobble Position of tRNAs" (1999)
"Structure of Transcription Elongation Complexes in Vivo" (1992)
"Trypanosome RNA Editing: Resolved" (1996)
"Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA" (1998)
"Site-Directed Hydroxyl Radical Probing of the rRNA Neighborhood of Ribosomal Protein S5" (1996)
"Shifting RNA Polymerase into Overdrive" (1999)
"A Mn$^{2+}$-Dependent Ribozyme" (1990)
"Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases" (1994)
"A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex" (1995)
"Toroidal Structure of $\lambda$-Exonuclease" (1997)
"RNA Editing Hints of a Remarkable Diversity in Gene Expression Pathways" (1996)
"Retention and 5' Cap Trimethylation of U3 snRNA in the Nucleus" (1994)
"Structures of Ternary Complexes of Rat DNA Polymerase $\beta$, a DNA Template-Primer, and ddCTP" (1994)
"$\beta$ Ribbon: A New DNA Recognition Motif" (1992)
"Solution Structure of a Two-Base DNA Bulge Complexed with an Enediyne Cleaving Analog" (1996)