WORDS
gene
disease
human
chromosome
cancer
genetic
genes
mutations
patients
university
mutation
alzheimers
normal
families
region
amyloid
genetics
breast
syndrome
department
linkage
medicine
individuals
markers
inherited
medical
app
affected
two
diseases
family
mice
dna
mouse
found
center
identified
usa
age
locus
tumor
linked
analysis
school
common
institute
protein
tumors
cause
molecular
familial
cases
studies
associated
fragile
onset
cancers
autosomal
research
disorder
loss
hospital
hereditary
defect
disorders
susceptibility
allele
suppressor
pathology
dominant
early
type
mutant
risk
genome
clinical
national
chromosomes
characterized
repeat
abnormalities
sporadic
rare
marker
colon
candidate
results
forms
degeneration
patient
development
brain
three
first
large
abnormal
mapped
identification
vol
science
RELATED TOPICS
gene dna mutations mutation mutant
genetic population populations data dna
insulin glucose mice diabetes hormone
hair cells inner hearing ear
cells leukemia cell abl patients
gene disease human chromosome cancer
disease patients drug new clinical
sequence dna genome sequences genes
genes development gene expression embryos
RELATED DOCUMENTS
"Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14" (1992)
"Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Disease Phenotype Determined by a DNA Polymorphism" (1992)
"Localization of a Breast Cancer Susceptibility Gene, BRCA2, to Chromosome 13q12-13" (1994)
"Mutations in the Dystrophin-Associated Protein $\gamma$-Sarcoglycan in Chromosome 13 Muscular Dystrophy" (1995)
"Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus" (1995)
"Inheritance of Proliferative Breast Disease in Breast Cancer Kindreds" (1990)
"Amyloid $\beta$ Protein Precursor Gene and Hereditary Cerebral Hemorrhage with Amyloidosis (Dutch)" (1990)
"Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22" (1992)
"Reduction in Size of the Myotonic Dystrophy Trinucleotide Repeat During Transmission" (1993)
"Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families" (1993)
"Myotonic Dystrophy Mutation: An Unstable CTG Repeat in the 3' Untranslated Region of the Gene" (1992)
"BRCA1 Mutations in Primary Breast and Ovarian Carcinomas" (1994)
"Genetic Mapping of a Locus Predisposing to Human Colorectal Cancer" (1993)
"Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis" (1998)
"Identification of a Gene That Causes Primary Open Angle Glaucoma" (1997)
"A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1" (1994)
"Clues to the Pathogenesis of Familial Colorectal Cancer" (1993)
"De Novo and Inherited Deletions of the 5q13 Region in Spinal Muscular Atrophies" (1994)
"Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21" (1990)
"Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search" (1996)
"Mutation in the ${\alpha}$-Synuclein Gene Indentified in Families with Parkinson's Disease" (1997)
"A Familial Alzheimer's Disease Locus on Chromosome I" (1995)
"Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients" (1990)
"Identification of a Gene Located at Chromosome 5q21 That is Mutated in Colorectal Cancers" (1991)
"Mutation of the Stargardt Disease Gene (ABCR) in Age-Related Macular Degeneration" (1997)
"Identification of the Tuberous Sclerosis Gene TSC1 on Chromosome 9q34" (1997)
"The Expanding World of Trinucleotide Repeats" (1996)
"Triplet Repeat Mutations in Human Disease" (1992)
"$\alpha$-Synuclein Gene and Parkinson's Disease" (1998)
"Positional Cloning of the Werner's Syndrome Gene" (1996)
"Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms" (1990)
"Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1" (1997)
"Human Cancer Syndromes: Clues to the Origin and Nature of Cancer" (1997)
"Molecular Genetics of Neurological Diseases" (1993)
"Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients" (1991)
"Genetic Complexity and Parkinson's Disease" (1997)
"Fragile X Genotype Characterized by an Unstable Region of DNA" (1991)
"Isolation of Sequences That Span the Fragile X and Identification of a Fragile X-Related CpG Island" (1991)
"Alzheimer's Disease and Possible Gene Interaction" (1994)
"Identification of ras Oncogene Mutations in the Stool of Patients with Curable Colorectal Tumors" (1992)
"Molecular Detection of Primary Bladder Cancer by Microsatellite Analysis" (1996)
"Wilms Tumor Locus on 11p13 Defined by Multiple CpG Island-Associated Transcripts" (1990)
"Candidate Gene Associated with a Mutation Causing Recessive Polycystic Kidney Disease in Mice" (1994)
"Linkage of a Cardiac Arrhythmia, the Long QT Syndrome, and the Harvey ras-1 Gene" (1991)
"Mapping of a Gene for Parkinson's Disease to Chromosome 4q21-q23" (1996)
"A Mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease" (1991)
"An Unstable Triplet Repeat in a Gene Related to Myotonic Muscular Dystrophy" (1992)
"Digenic Retinitis Pigmentosa Due to Mutations at the Unlinked Peripherin/ RDS and ROM1 Loci" (1994)
"Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure" (1998)
"Mouse Models of Tumor Development in Neurofibromatosis Type 1" (1999)
"Polar Overdominance at the Ovine callipyge Locus" (1996)
"Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene" (1993)
"Mutation of a mutL Homolog in Hereditary Colon Cancer" (1994)
"Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type" (1990)
"Muscular Dystrophies: Diseases of the Dystrophin-Glycoprotein Complex" (1995)
"ApoE, Amyloid, and Alzheimer's Disease" (1994)
"Mutations in the Gene Encoding Cystatin B in Progressive Myoclonus Epilepsy (EPM1)" (1996)
"Association Between X-Linked Mixed Deafness and Mutations in the POU Domain Gene POU3F4" (1995)
"A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase" (1995)
"Alzheimer's Disease: Genotypes, Phenotype, and Treatments" (1997)
"Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome" (1999)
"Rates of p16 (MTS1) Mutations in Primary Tumors with 9p Loss" (1994)
"Gene for Familial Psoriasis Susceptibility Mapped to the Distal End of Human Chromosome 17q" (1994)
"Connexin Mutations in X-Linked Charcot-Marie-Tooth Disease" (1993)
"Thymidine Phosphorylase Gene Mutations in MNGIE, a Human Mitochondrial Disorder" (1999)
"Inactivation of the Mouse Huntington's Disease Gene Homolog Hdh" (1995)
"Implications of FRA16A Structure for the Mechanism of Chromosomal Fragile Site Genesis" (1994)
"Breast Cancer: Two Steps Closer to Understanding" (1990)
"An Allele of COL9A2 Associated with Intervertebral Disc Disease" (1999)
"Instability of a 550-Base Pair DNA Segment and Abnormal Methylation in Fragile X Syndrome" (1991)
"Identification of Mutations in the COL4A5 Collagen Gene in Alport Syndrome" (1990)
"Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17" (1998)
"Proliferative Breast Disease: Diagnosis and Implications" (1991)
"Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples" (1991)
"A Potassium Channel Mutation in Neonatal Human Epilepsy" (1998)
"Cystic Fibrosis: Molecular Biology and Therapeutic Implications" (1992)
"A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse" (1990)
"New Colon Cancer Gene Discovered" (1993)
"Appendix: A Comprehensive Genetic Linkage Map of the Human Genome" (1992)
"Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain" (1997)
"Evidence of Genetic Heterogeneity in the Long QT Syndrome" (1993)
"Identification of a Chromosome 18q Gene That is Altered in Colorectal Cancers" (1990)
"Detecting Alzheimer's Disease" (1995)
"Familial Alzheimer's Linked To Chromosome 14 Gene" (1992)
"Mutation Identified as a Possible Cause of Alzheimer's Desease" (1991)
"Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene" (1992)
"Genome Maps 7: The Human Transcript Map" (1996)
"Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis" (1997)
"Tissue, Developmental, and Tumor-Specific Expression of Divergent Transcripts in Wilms Tumor" (1990)
"Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion" (1996)
"The Skeletal Muscle Chloride Channel in Dominant and Recessive Human Myotonia" (1992)
"Microsatellite Instability in Cancer of the Proximal Colon" (1993)
"Alzheimer's Disease: A Cell Biological Perspective" (1992)
"A Comprehensive Human Linkage Map with Centimorgan Density" (1994)
"Alzheimer's Disease: The Amyloid Cascade Hypothesis" (1992)
"Mutation of a Gene Encoding a Protein with Extracellular Matrix Motifs in Usher Syndrome Type IIa" (1998)
"Rapid Induction of Alzheimer A$\beta$ Amyloid Formation by Zinc" (1994)
"Abnormal Behavior Associated with a Point Mutation in the Structural Gene for Monoamine Oxidase A" (1993)
"Link to Hereditary Melanoma Brightens Mood for p16 Gene" (1994)
"On the Molecular Genetics of Retinitis Pigmentosa" (1992)