WORDS
protein
cell
kinase
activity
cycle
p53
cells
cyclin
yeast
transcription
phosphorylation
activation
fig
gene
dependent
dna
proteins
phosphatase
expression
phase
binding
arrest
factor
control
regulation
human
type
domain
kinases
transcriptional
complex
function
extracts
usa
regulated
regulatory
cdc2
response
growth
wild
cellular
department
two
required
associated
vitro
phosphorylated
genes
mutant
specific
subunit
synthesis
inhibition
cdk
progression
promoter
university
cyclins
gal4
inhibitor
interaction
gst
addressed
mitosis
checkpoint
correspondence
role
damage
biology
cancer
essential
complexes
identified
p21
institute
vivo
cdk2
tumor
suppressor
serine
phosphate
results
terminal
mammalian
molecular
induced
family
induction
threonine
active
factors
e2f
mitotic
product
activated
atm
site
division
cdks
cerevisiae
RELATED TOPICS
gene dna mutations mutation mutant
protein proteins binding domain membrane
protein cell kinase activity cycle
dna replication cell chromosome chromosomes
kinase protein tyrosine activation cells
protein sequence amino cdna fig
RELATED DOCUMENTS
"Dephosphorylation of Cdk2 Thr$^{160}$ by the Cyclin-Dependent Kinase-Interacting Phosphatase KAP in the Absence of Cyclin" (1995)
"Phosphate-Regulated Inactivation of the Kinase PHO80-PHO85 by the CDK Inhibitor PHO81" (1994)
"Direct Inhibition of the Yeast Cyclin-Dependent Kinase Cdc28-Cln by Far1" (1994)
"Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint" (1998)
"The PCL2 (ORFD)-PHO85 Cyclin-Dependent Kinase Complex: A Cell Cycle Regulator in Yeast" (1994)
"Negative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-$\beta$" (1993)
"Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85" (1994)
"Mitotic and G$_2$ Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216" (1997)
"Regulation of the Human hsp70 Promoter by p53" (1993)
"Regulation of PH04 Nuclear Localization by the PH080-PH085 Cyclin-CDK Complex" (1996)
"Requirement for p53 and p21 to Sustain G$_2$ Arrest After DNA Damage" (1998)
"Rapid Degradation of the G$_1$ Cyclin CIn2 Induced by CDK-Dependent Phosphorylation" (1996)
"Cell Cycle Regulation of Histone H1 Kinase Activity Associated with the Adenoviral Protein E1A" (1991)
"Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27" (1995)
"Regulation of NF-$\kappa$B by Cyclin-Dependent Kinases Associated with the p300 Coactivator" (1997)
"An Inhibitor of p34$^{CDC28}$ Protein Kinase Activity from Saccharomyces cerevisiae" (1993)
"Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase" (1997)
"Association of Human Cyclin E with a Periodic G$_1$-S Phase Protein Kinase" (1992)
"Formation and Activation of a Cyclin E-cdk2 Complex During the G$_1$ Phase of the Human Cell Cycle" (1992)
"Cell Cycle Control by a Complex of the Cyclin HCS26 (PCL1) and the Kinase PHO85" (1994)
"Nondissociation of GAL4 and GAL80 in Vivo After Galactose Induction" (1992)
"Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control" (1993)
"Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25" (1997)
"Inactivation of the p34$^{cdc2}$-Cyclin B Complex by the Human WEE1 Tyrosine Kinase" (1992)
"Complementation of the Mitotic Activator, p80$^{cdc25}$, by a Human Protein-Tyrosine Phosphatase" (1990)
"Interaction Between Human Cyclin A and Adenovirus E1A-Associated p107 Protein" (1992)
"Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase" (1998)
"Purification and Cloning of a Protein Kinase That Phosphorylates and Activates the Polo-Like Kinase Plx1" (1998)
"A Role for the Transcription Factors Mbp1 and Swi4 in Progression from G1 to S Phase" (1993)
"Replication Checkpoint Enforced by Kinases Cds1 and Chk1" (1998)
"E2F: A Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins" (1992)
"Reconstitution of G$_1$ Cyclin Ubiquitination with Complexes Containing SCF$^{Grr1}$ and Rbx1" (1999)
"A DNA Damage Checkpoint Meets the Cell Cycle Engine" (1997)
"Gene Expression and the Cell Cycle: A Family Affair" (1993)
"Requirement of p27$^{Kip1}$ for Restriction Point Control of the Fibroblast Cell Cycle" (1996)
"Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin" (1997)
"Roles of Phosphorylation Sites in Regulating Activity of the Transcription Factor Pho4" (1999)
"Control of the DNA Damage Checkpoint by Chk1 and Rad53 Protein Kinases Through Distinct Mechanisms" (1999)
"Requirement for Cdk2 in Cytostatic Factor-Mediated Metaphase II Arrest" (1993)
"Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53" (1998)
"Translational Control of p27$^{Kip1}$ Accumulation During the Cell Cycle" (1996)
"Cancer Cell Cycles" (1996)
"Inhibition of Myogenic Differentiation in Proliferating Myoblasts by Cyclin D1-Dependent Kinase" (1995)
"The Expanding Role of Cell Cycle Regulators" (1998)
"Activation of Gal4p by Galactose-Dependent Interaction of Galactokinase and Gal80p" (1996)
"Cell Cycle Control of DNA Replication by a Homologue from Human Cells of the p34$^{cdc2}$ Protein Kinase" (1990)
"Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members" (1993)
"Myt1: A Membrane-Associated Inhibitory Kinase that Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15" (1995)
"Dependence of Cyclin E-CDK2 Kinase Activity on Cell Anchorage" (1996)
"Inhibition of Ras-Induced Proliferation and Cellular Transformation by p16$^{INK4}$" (1995)
"Malignant Transformation by a Mutant of the IFN-Inducible dsRNA-Dependent Protein Kinase" (1992)
"rad-Dependent Response of the chk1-Encoded Protein Kinase at the DNA Damage Checkpoint" (1996)
"Cyclin-Dependent Regulation of G$_1$ in Mammalian Fibroblasts" (1993)
"Association of cdk2 Kinase with the Transcription Factor E2F During S Phase" (1992)
"p53-Independent Expression of p21$^{Cip1}$ in Muscle and Other Terminally Differentiating Cells" (1995)
"Phosphorylation of Sic1p by G$_1$ Cdk Required for Its Degradation and Entry into S Phase" (1997)
"Rad9 Comes of Age" (1998)
"Identification of Yeast Rho1p GTPase as a Regulatory Subunit of 1,3-$/beta$-Glucan Synthase" (1996)
"Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression" (1992)
"Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts" (1996)
"Pharmacological Rescue of Mutant p53 Conformation and Function" (1999)
"SBF Cell Cycle Regulator as a Target of the Yeast PKC-MAP Kinase Pathway" (1997)
"Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen" (1994)
"Blockage by Adenovirus E4orf6 of Transcriptional Activation by the p53 Tumor Suppressor" (1996)
"A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression" (1993)
"Induction of Metaphase Arrest in Cleaving Xenopus Embryos by the Protein Kinase p90$^{Rsk}$" (1999)
"Induction of Metaphase Arrest in Cleaving Xenopus Embryos by MAP Kinase" (1993)
"cdc2 Gene Expression at the G$_1$ to S Transition in Human T Lymphocytes" (1990)
"Ability of the c-mos Product to Associate with and Phosphorylate Tubulin" (1991)
"Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage" (1998)
"Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B" (1997)
"Control of I$\kappa$B-$\alpha$ Proteolysis by Site-Specific, Signal-Induced Phosphorylation" (1995)
"Regulation of Protein Serine-Threonine Phosphatase Type-2A by Tyrosine Phosphorylation" (1992)
"Presence of a Potent Transcription Activating Sequence in the p53 Protein" (1990)
"Differential Phosphorylation of c-Abl in Cell Cycle Determined by $cdc2$ Kinase and Phosphatase Activity" (1990)
"Linkage of Replication to Start by the Cdk Inhibitor Sic 1" (1996)
"Rho1p, a Yeast Protein at the Interface Between Cell Polarization and Morphogenesis" (1996)
"Regulation of Activity of a Transcriptional Anti-Terminator in E. coli by Phosphorylation in Vivo" (1990)
"A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK" (1996)
"The Protein Kinase p90 Rsk as an Essential Mediator of Cytostatic Factor Activity" (1999)
"Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks" (1999)
"Inhibition of the Interferon-Inducible Protein Kinase PKR by HCV E2 Protein" (1999)
"Activation of RET as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B" (1995)
"Cell Cycle Regulation of E2F Site Occupation In vivo" (1996)
"Inhibition of HIV-1 Replication in Lymphocytes by Mutants of the Rev Cofactor eIF-5A" (1996)
"Requirement for cAMP-PKA Pathway Activation by M Phase-Promoting Factor in the Transition from Mitosis to Interphase" (1996)
"Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53" (1990)
"Checkpoints Take the Next Step" (1996)
"Interaction of p107 with Cyclin A Independent of Complex Formation with Viral Oncoproteins" (1992)
"Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD" (1995)
"The ras Oncoprotein and M-Phase Activity" (1991)
"Interaction of Papillomavirus E6 Oncoproteins with a Putative Calcium-Binding Protein" (1995)
"Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein" (1993)
"Control of the Interferon-Induced 68-Kilodalton Protein Kinase by the HIV-1 tat Gene Product" (1990)
"Researchers Find New Role for Cell Cycle Proteins" (1994)
"PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation" (1994)
"Mitotic Repression of RNA Polymerase III Transcription in Vitro Mediated by Phosphorylation of a TFIIIB Component" (1994)
"Transcriptional Activation by Wild-Type But Not Transforming Mutants of the p53 Anti-Oncogene" (1990)
"In Vitro Transcriptional Activation by a Metabolic Intermediate: Activation by Leu3 Depends on $\alpha$-Isopropylmalate" (1992)
"Regulation of RAD53 by the ATM-Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint Pathways" (1996)