Mendelian Transmission 1: Forward Modeling |
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In a single problem:
- Students generate all possible genotypes (for one gene) when two parents of the same phenotypes are crossed and describe phenotypes and genotypes of resulting offspring.
- Students do the same for two parents of different phenotypes.
- Students summarize possible inferences from offspring phenotypes to parental genotypes for purposes of experiment design and interpretation.
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Mendelian Transmission 2: Experiment Design and Interpretation |
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Students are given three strains with one or two phenotype(s) determined by a single gene. Students design and interpret crosses to determine the genotypes of the three strains.
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Gene Interaction and Epistasis |
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Mendelian principles are extended to multiple alleles and to two genes with gene interactions (epistasis). Students cross three true-breeding strains with different phenotypes and perform F1 intercrosses. From the phenotypes of the F1 and F2 progeny, students decide how many genes are segregating and identify the genotypes of the various parental strains and the F1 and F2 offspring.
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