02-718: Spring 2017:
This is course on the algorithms and computational methods used in modern medicine. The topics to be covered include computational strategies for advancing personalized medicine, pharmacogenomics for predicting individual drug responses, metagenomics for learning the role of the microbiome in human health, mining electronic medical records to identify disease phenotypes, and case studies in complex human diseases such as cancer and asthma. We will discuss how machine learning methodologies such as regression, classification, clustering, semi-supervised learning, probabilistic modeling, and time-series modeling are being used to analyze a variety of datasets collected by clinicians. Class sessions will consist of lectures, discussions of papers from the literature, and guest presentations by clinicians and other domain experts. Grading will be based on homework assignments and a project. This course is self contained. There are no prerequisites.
Previously offered: Spring 2016
Next offered: Fall 2018
Automation of Biological Research
02-450 and 02-750: Spring 2018:
This is a course in the application of Active Learning, Robotics, and High-Throughput/High-Content assays to accelerate biological discovery.
Previously offered: Fall 2014, Fall 2015, Fall 2016, Fall 2017
Cell and Systems Modeling
02-730: Fall 2015:
This is an introductory course in Systems Biology focusing on the development, simulation, and analysis of mechanistic models of biological systems.
Previously offered: Spring 2011, Spring 2012, Spring 2013, Fall 2013, Fall 2014
Algorithms for Computational Structural Biology
02-721 (formerly 15-879): Spring 2014
This course is an introductory survey of the algorithmic techniques used in the field of structural biology.
Previously offered: Fall 2004, Spring 2007, Spring 2010
Advanced Algorithms for Computational Structural Biology
02-722: Fall 2012 Guest-taught by Prof. Ilyin
This is a seminar-style course on the current literature in computational structural biology.
Pre-req: 15-879A, or permission of the instructor
Previously offered: Spring 2005, Fall 2005
Computational Biology Journal Club
02-730: Spring 2015:
This is a journal club focusing on the recent literature in Computational Biology