HHsim - A Graphical Hodgkin-Huxley Simulator in MATLAB Version 3.7 - August 27, 2025 Copyright (C) 2000,2001,2002,2003,2007,2012,2017,2025 by David S. Touretzky, Mark V. Albert, Nathaniel D. Daw, Alok Ladsariya and Mahtiyar Bonakdarpour. This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA ================================================================ HHsim is a graphical simulation of a section of excitable neuronal membrane, using the Hodgkin-Huxley equations. Design by David S. Touretzky Coding by David S. Touretzky, Mark V. Albert, Nathaniel D. Daw, Alok Ladsariya and Mahtiyar Bonakdarpour Contact information: David S. Touretzky Computer Science Department Carnegie Mellon University Pittsburgh, PA 15213-3891 email: dst@cs.cmu.edu ================================================================ RUNNING HHSIM From Matlab source only: 1) start up Matlab 2) cd to the directory holding the source code 3) type "hhsim" ================================================================ Click on the purple Stim1 or Stim2 buttons to inject a depolarizing or hyperpolarizing current stimulus. Click on the Membrane, Channels, Stimuli or Drugs buttons to view and modify the simulation parameters. This program was inspired by earlier BASIC and C programs by Professor David Wood, and lecture notes by Professor Bard Ermentrout, both at the University of Pittsburgh. Thanks to Professor Jon Johnson at the University of Pittsburgh for many helpful suggestions for improving the user interface. This work was supported in part by National Science Foundation grant DGE-9987588. Any opinions, conclusions, or recommendations expressed herein are those of the authors and do not necessarily reflect the views of the National Science Foundation.